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| Human cd271 (aa 29 – 250) |
| CD271 Swiss Prot | | P08138 |
| CD271 Protein names | | Tumor necrosis factor receptor superfamily member 16 (Gp80-LNGFR) (Low affinity neurotrophin receptor p75NTR) (Low-affinity nerve growth factor receptor) (NGF receptor) (p75 ICD) (CD antigen CD271) |
| CD271 Gene names | | NGFR TNFRSF16 |
| Organism | | Human |
| CD271 Entry name | | TNR16_HUMAN |
| CD271 Codon optimized cDNA Clone |
| CD271 cDNA Cat | | RPV0446 |
| cDNA Tag | | cDNA CD271 contains A 6x histidine tag |
| Condon optimized CD271 cDNA Formulation | | Liquid |
| Condon optimized CD271 cDNA Storage | | Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Condon optimized CD271 cDNA Applications | | Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function. |
| Recombinant CD271 Protein |
| Recombinant CD271 Protein Cat | | PV0446 |
| CD271 Protein Source | | Recombinant protein |
| Recombinant CD271 Protein Applications | | Western Blot, may be used for other applications determined by user |
| Recombinant CD271 Protein Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Recombinant CD271 Protein Activity | | N/A |
| Recombinant protein Tag | | Recombinant CD271 contains A 6x histidine tag |
| Recombinant CD271 Protein Formulation | | Liquid |
| Recombinant CD271 Protein Storage | | Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant CD271 Protein or cDNA | | For pricing and availability, Click Here >>> |
| CD271 SUBUNIT | | SUBUNIT: Homodimer; disulfide-linked. Interacts with p75NTR-associated cell death executor. Interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9. Interacts through TRAF6 with SQSTM1 which bridges NGFR to NTRK1. Interacts with BEX1 and NGFRAP1/BEX3. Interacts with KIDINS220 and NTRK1. Can form a ternary complex with NTRK1 and KIDINS220 and this complex is affected by the expression levels of KIDINS220. An increase in KIDINS220 expression leads to a decreased association of |
| | NGFR and NTRK1 (By similarity). Interacts with LINGO1. |
| CD271 Subcellular locations | | SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. |
| CD271 FUNCTION According to UniProtKB Swiss Prot | | Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. |
| CD271 Sequence databases | | EMBL | DDBJ | GenBank |
| CD271 3D structure databases | | ModBase |
| CD271 Protein protein interaction databases | | STRING |
| CD271 Proteomic databases | | PRIDE |
| CD271 Genome annotation databases | | Ensembl | GeneID | KEGG | UCSC |
| CD271 Organism specific databases | | CTD | MGI |
| CD271 Phylogenomic databases | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| CD271 Gene expression databases | | Bgee | ArrayExpress | Genevestigator |
| CD271 Family and domain databases | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |