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Human cd271 (aa 29 – 250)
CD271 Swiss Prot
P08138
CD271 Protein names
Tumor necrosis factor receptor superfamily member 16 (Gp80-LNGFR) (Low affinity neurotrophin receptor p75NTR) (Low-affinity nerve growth factor receptor) (NGF receptor) (p75 ICD) (CD antigen CD271)
CD271 Gene names
NGFR TNFRSF16
Organism
Human
CD271 Entry name
TNR16_HUMAN
CD271 Codon optimized cDNA Clone
CD271 cDNA Cat
RPV0446
cDNA Tag
cDNA CD271 contains A 6x histidine tag
Condon optimized CD271 cDNA Formulation
Liquid
Condon optimized CD271 cDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Condon optimized CD271 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function.
Recombinant CD271 Protein
Recombinant CD271 Protein Cat
PV0446
CD271 Protein Source
Recombinant protein
Recombinant CD271 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant CD271 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant CD271 Protein Activity
N/A
Recombinant protein Tag
Recombinant CD271 contains A 6x histidine tag
Recombinant CD271 Protein Formulation
Liquid
Recombinant CD271 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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CD271 SUBUNIT
SUBUNIT: Homodimer; disulfide-linked. Interacts with p75NTR-associated cell death executor. Interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9. Interacts through TRAF6 with SQSTM1 which bridges NGFR to NTRK1. Interacts with BEX1 and NGFRAP1/BEX3. Interacts with KIDINS220 and NTRK1. Can form a ternary complex with NTRK1 and KIDINS220 and this complex is affected by the expression levels of KIDINS220. An increase in KIDINS220 expression leads to a decreased association of

NGFR and NTRK1 (By similarity). Interacts with LINGO1.
CD271 Subcellular locations
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
CD271 FUNCTION According to UniProtKB Swiss Prot
Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells.
CD271 Sequence databases
EMBL DDBJ GenBank
CD271 3D structure databases
ModBase
CD271 Protein protein interaction databases
STRING
CD271 Proteomic databases
PRIDE
CD271 Genome annotation databases
Ensembl GeneID KEGG UCSC
CD271 Organism specific databases
CTD MGI
CD271 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
CD271 Gene expression databases
Bgee ArrayExpress Genevestigator
CD271 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY