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| Human CD274 (aa 19 – 238) |
| CD274 Swiss Prot | | Q9NZQ7 |
| CD274 Protein names | | Programmed cell death 1 ligand 1 (PD-L1) (PDCD1 ligand 1) (Programmed death ligand 1) (B7 homolog 1) (B7-H1) (CD antigen CD274) |
| CD274 Gene names | | CD274 B7H1 PDCD1L1 PDCD1LG1 PDL1 |
| Organism | | Human |
| CD274 Entry name | | PD1L1_HUMAN |
| CD274 Codon optimized cDNA Clone |
| CD274 cDNA Cat | | RPV0455 |
| cDNA Tag | | cDNA CD274 contains A 6x histidine tag |
| Condon optimized CD274 cDNA Formulation | | Liquid |
| Condon optimized CD274 cDNA Storage | | Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Condon optimized CD274 cDNA Applications | | Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function. |
| Recombinant CD274 Protein |
| Recombinant CD274 Protein Cat | | PV0455 |
| CD274 Protein Source | | Recombinant protein |
| Recombinant CD274 Protein Applications | | Western Blot, may be used for other applications determined by user |
| Recombinant CD274 Protein Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Recombinant CD274 Protein Activity | | N/A |
| Recombinant protein Tag | | Recombinant CD274 contains A 6x histidine tag |
| Recombinant CD274 Protein Formulation | | Liquid |
| Recombinant CD274 Protein Storage | | Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant CD274 Protein or cDNA | | For pricing and availability, Click Here >>> |
| CD274 SUBUNIT | | SUBUNIT: Interacts with PDCD1. |
| CD274 Subcellular locations | | SUBCELLULAR LOCATION: Isoform 1: Cell membrane; Single-pass type I membrane protein. ; SUBCELLULAR LOCATION: Isoform 2: Endomembrane system; Single-pass type I membrane protein. |
| CD274 FUNCTION According to UniProtKB Swiss Prot | | Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production. |
| CD274 Sequence databases | | EMBL | DDBJ | GenBank |
| CD274 3D structure databases | | ModBase |
| CD274 Protein protein interaction databases | | STRING |
| CD274 Proteomic databases | | PRIDE |
| CD274 Genome annotation databases | | Ensembl | GeneID | KEGG | UCSC |
| CD274 Organism specific databases | | CTD | MGI |
| CD274 Phylogenomic databases | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| CD274 Gene expression databases | | Bgee | ArrayExpress | Genevestigator |
| CD274 Family and domain databases | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |
