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| Mouse cd275 (aa 47 – 277) |
| CD275 Swiss Prot | | Q9JHJ8 |
| CD275 Protein names | | ICOS ligand (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (LICOS) (CD antigen CD275) |
| CD275 Gene names | | Icoslg B7h2 B7rp1 Icosl |
| Organism | | Mouse |
| CD275 Entry name | | ICOSL_MOUSE |
| CD275 Codon optimized cDNA Clone |
| CD275 cDNA Cat | | RPV0459 |
| cDNA Tag | | cDNA CD275 contains A 6x histidine tag |
| Condon optimized CD275 cDNA Formulation | | Liquid |
| Condon optimized CD275 cDNA Storage | | Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Condon optimized CD275 cDNA Applications | | Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function. |
| Recombinant CD275 Protein |
| Recombinant CD275 Protein Cat | | PV0459 |
| CD275 Protein Source | | Recombinant protein |
| Recombinant CD275 Protein Applications | | Western Blot, may be used for other applications determined by user |
| Recombinant CD275 Protein Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Recombinant CD275 Protein Activity | | N/A |
| Recombinant protein Tag | | Recombinant CD275 contains A 6x histidine tag |
| Recombinant CD275 Protein Formulation | | Liquid |
| Recombinant CD275 Protein Storage | | Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant CD275 Protein or cDNA | | For pricing and availability, Click Here >>> |
| CD275 SUBUNIT | | - |
| CD275 Subcellular locations | | SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. |
| CD275 FUNCTION According to UniProtKB Swiss Prot | | Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function. During pregnancy, may function to skew the cytokine of maternal T-cells toward |
| | immunoprotective Th2 phenotype. |
| CD275 Sequence databases | | EMBL | DDBJ | GenBank |
| CD275 3D structure databases | | ModBase |
| CD275 Protein protein interaction databases | | STRING |
| CD275 Proteomic databases | | PRIDE |
| CD275 Genome annotation databases | | Ensembl | GeneID | KEGG | UCSC |
| CD275 Organism specific databases | | CTD | MGI |
| CD275 Phylogenomic databases | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| CD275 Gene expression databases | | Bgee | ArrayExpress | Genevestigator |
| CD275 Family and domain databases | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |
