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| Human cd281 (aa 25 – 580) |
| CD281 Swiss Prot | | Q15399 |
| CD281 Protein names | | Toll-like receptor 1 (Toll/interleukin-1 receptor-like protein) (TIL) (CD antigen CD281) |
| CD281 Gene names | | TLR1 KIAA0012 |
| Organism | | Human |
| CD281 Entry name | | TLR1_HUMAN |
| CD281 Codon optimized cDNA Clone |
| CD281 cDNA Cat | | RPV0474 |
| cDNA Tag | | cDNA CD281 contains A 6x histidine tag |
| Condon optimized CD281 cDNA Formulation | | Liquid |
| Condon optimized CD281 cDNA Storage | | Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Condon optimized CD281 cDNA Applications | | Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function. |
| Recombinant CD281 Protein |
| Recombinant CD281 Protein Cat | | PV0474 |
| CD281 Protein Source | | Recombinant protein |
| Recombinant CD281 Protein Applications | | Western Blot, may be used for other applications determined by user |
| Recombinant CD281 Protein Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Recombinant CD281 Protein Activity | | N/A |
| Recombinant protein Tag | | Recombinant CD281 contains A 6x histidine tag |
| Recombinant CD281 Protein Formulation | | Liquid |
| Recombinant CD281 Protein Storage | | Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant CD281 Protein or cDNA | | For pricing and availability, Click Here >>> |
| CD281 SUBUNIT | | SUBUNIT: Binds MYD88 (via TIR domain). Interacts with CNPY3 (By similarity). Interacts (via extracellular domain) with TLR2. Ligand binding induces the formation of a heterodimer with TLR2. |
| CD281 Subcellular locations | | SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein (By similarity). Cytoplasmic vesicle, phagosome membrane; Single-pass type I membrane protein (By similarity). |
| CD281 FUNCTION According to UniProtKB Swiss Prot | | Participates in the innate immune response to microbial agents. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). |
| CD281 Sequence databases | | EMBL | DDBJ | GenBank |
| CD281 3D structure databases | | ModBase |
| CD281 Protein protein interaction databases | | STRING |
| CD281 Proteomic databases | | PRIDE |
| CD281 Genome annotation databases | | Ensembl | GeneID | KEGG | UCSC |
| CD281 Organism specific databases | | CTD | MGI |
| CD281 Phylogenomic databases | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| CD281 Gene expression databases | | Bgee | ArrayExpress | Genevestigator |
| CD281 Family and domain databases | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |
