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| Mouse cd283 (aa 26 – 426) |
| CD283 Swiss Prot | | Q99MB1 |
| CD283 Protein names | | Toll-like receptor 3 (CD antigen CD283) |
| CD283 Gene names | | Tlr3 |
| Organism | | Mouse |
| CD283 Entry name | | TLR3_MOUSE |
| CD283 Codon optimized cDNA Clone |
| CD283 cDNA Cat | | RPV0481 |
| cDNA Tag | | cDNA CD283 contains A 6x histidine tag |
| Condon optimized CD283 cDNA Formulation | | Liquid |
| Condon optimized CD283 cDNA Storage | | Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Condon optimized CD283 cDNA Applications | | Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function. |
| Recombinant CD283 Protein |
| Recombinant CD283 Protein Cat | | PV0481 |
| CD283 Protein Source | | Recombinant protein |
| Recombinant CD283 Protein Applications | | Western Blot, may be used for other applications determined by user |
| Recombinant CD283 Protein Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Recombinant CD283 Protein Activity | | N/A |
| Recombinant protein Tag | | Recombinant CD283 contains A 6x histidine tag |
| Recombinant CD283 Protein Formulation | | Liquid |
| Recombinant CD283 Protein Storage | | Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant CD283 Protein or cDNA | | For pricing and availability, Click Here >>> |
| CD283 SUBUNIT | | SUBUNIT: Binds MYD88 via their respective TIR domains. Interacts with TICAM1. Homodimer formation is triggered by ligand binding and is required for TLR3 signaling. Binding of double-stranded RNA is required for the interaction with SRC (By similarity). Interacts (via transmembrane domain) with UNC93B1. |
| CD283 Subcellular locations | | SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endosome membrane (By similarity). |
| CD283 FUNCTION According to UniProtKB Swiss Prot | | Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific of microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). |
| CD283 Sequence databases | | EMBL | DDBJ | GenBank |
| CD283 3D structure databases | | ModBase |
| CD283 Protein protein interaction databases | | STRING |
| CD283 Proteomic databases | | PRIDE |
| CD283 Genome annotation databases | | Ensembl | GeneID | KEGG | UCSC |
| CD283 Organism specific databases | | CTD | MGI |
| CD283 Phylogenomic databases | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| CD283 Gene expression databases | | Bgee | ArrayExpress | Genevestigator |
| CD283 Family and domain databases | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |
