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| Human cd111 (aa 31 – 355) |
| CD111 Swiss Prot | | Q15223 |
| CD111 Protein names | | Poliovirus receptor-related protein 1 (Herpes virus entry mediator C) (Herpesvirus entry mediator C) (HveC) (Herpesvirus Ig-like receptor) (HIgR) (Nectin-1) (CD antigen CD111) |
| CD111 Gene names | | PVRL1 HVEC PRR1 |
| Organism | | Human |
| CD111 Entry name | | PVRL1_HUMAN |
| CD111 Codon optimized cDNA Clone |
| CD111 cDNA Cat | | RPV0049 |
| cDNA Tag | | cDNA CD111 contains A 6x histidine tag |
| Condon optimized CD111 cDNA Formulation | | Liquid |
| Condon optimized CD111 cDNA Storage | | Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Condon optimized CD111 cDNA Applications | | Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function. |
| Recombinant CD111 Protein |
| Recombinant CD111 Protein Cat | | PV0049 |
| CD111 Protein Source | | Recombinant protein |
| Recombinant CD111 Protein Applications | | Western Blot, may be used for other applications determined by user |
| Recombinant CD111 Protein Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Recombinant CD111 Protein Activity | | N/A |
| Recombinant protein Tag | | Recombinant CD111 contains A 6x histidine tag |
| Recombinant CD111 Protein Formulation | | Liquid |
| Recombinant CD111 Protein Storage | | Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant CD111 Protein or cDNA | | For pricing and availability, Click Here >>> |
| CD111 SUBUNIT | | SUBUNIT: Can form trans-heterodimers with PVRL3/nectin-3 and with PVRL4/nectin-4. Interacts (via C-terminus) with afadin (via PDZ domain); this interaction recruits PVRL1 to cadherin-based adherens junctions. Interacts with integrin alphaV/beta3. Interacts with herpes simplex virus 1 (HHV-1), herpes simplex virus 2 (HHV-2), and pseudorabies virus (PRV) envelope glycoprotein D; functions as an entry receptor for these viruses. |
| CD111 Subcellular locations | | SUBCELLULAR LOCATION: Isoform Alpha: Cell membrane; Single-pass type I membrane protein. ; SUBCELLULAR LOCATION: Isoform Delta: Cell membrane; Single-pass type I membrane protein. ; SUBCELLULAR LOCATION: Isoform Gamma: Secreted. |
| CD111 FUNCTION According to UniProtKB Swiss Prot | | Promotes cell-cell contacts by forming homophilic or heterophilic trans-dimers. Heterophilic interactions have been detected between PVRL1/nectin-1 and PVRL3/nectin-3 and between PVRL1/nectin-1 and PVRL4/nectin-4. |
| CD111 Sequence databases | | EMBL | DDBJ | GenBank |
| CD111 3D structure databases | | ModBase |
| CD111 Protein protein interaction databases | | STRING |
| CD111 Proteomic databases | | PRIDE |
| CD111 Genome annotation databases | | Ensembl | GeneID | KEGG | UCSC |
| CD111 Organism specific databases | | CTD | MGI |
| CD111 Phylogenomic databases | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| CD111 Gene expression databases | | Bgee | ArrayExpress | Genevestigator |
| CD111 Family and domain databases | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |
