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| Mouse cd29 (aa 21 – 421) |
| CD29 Swiss Prot | | P09055 |
| CD29 Protein names | | Integrin beta-1 (Fibronectin receptor subunit beta) (VLA-4 subunit beta) (CD antigen CD29) |
| CD29 Gene names | | Itgb1 |
| Organism | | Mouse |
| CD29 Entry name | | ITB1_MOUSE |
| CD29 Codon optimized cDNA Clone |
| CD29 cDNA Cat | | RPV0494 |
| cDNA Tag | | cDNA CD29 contains A 6x histidine tag |
| Condon optimized CD29 cDNA Formulation | | Liquid |
| Condon optimized CD29 cDNA Storage | | Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Condon optimized CD29 cDNA Applications | | Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function. |
| Recombinant CD29 Protein |
| Recombinant CD29 Protein Cat | | PV0494 |
| CD29 Protein Source | | Recombinant protein |
| Recombinant CD29 Protein Applications | | Western Blot, may be used for other applications determined by user |
| Recombinant CD29 Protein Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Recombinant CD29 Protein Activity | | N/A |
| Recombinant protein Tag | | Recombinant CD29 contains A 6x histidine tag |
| Recombinant CD29 Protein Formulation | | Liquid |
| Recombinant CD29 Protein Storage | | Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant CD29 Protein or cDNA | | For pricing and availability, Click Here >>> |
| CD29 SUBUNIT | | SUBUNIT: Heterodimer of an alpha and a beta subunit. Beta-1 associates with either alpha-1, alpha-2, alpha-3, alpha-4, alpha-5, alpha-6, alpha-7, alpha-8, alpha-9, alpha-10, alpha-11 or alpha-V. Binds LGALS3BP and ITGB1BP3, when associated with alpha-7, but not with alpha-5. Interacts with FLNA, FLNB, FLNC and RANBP9. Interacts with KRT1 in the presence of GNB2L1 and SRC (By similarity). Interacts with RAB21. Interacts (via the cytoplasmic region) with RAB25 (via the hypervariable |
| | C-terminal region) (By similarity). |
| CD29 Subcellular locations | | SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein (By similarity). Melanosome (By similarity). |
| CD29 FUNCTION According to UniProtKB Swiss Prot | | Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha-4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha-4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions |
| | of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin alpha-1/beta-1, alpha-2/beta-1, alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin. Integrin alpha-4/beta-1 is a receptor for VCAM1 and recognizes the |
| | sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. Integrin alpha-3/beta-1 is a receptor for epiligrin, thrombospondin and CSPG4. |
| | Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. When associated |
| | with alpha-7/beta-1 integrin, regulates cell adhesion and laminin matrix deposition. Involved in promoting endothelial cell motility and angiogenesis. May be involved in up-regulation of the activity of kinases such as PKC via binding to KRT1. |
| | Together with KRT1 and GNB2L1, serves as a platform for SRC activation or inactivation. Plays a mechanistic adhesive role during telophase, required for the successful completion of cytokinesis. |
| CD29 Sequence databases | | EMBL | DDBJ | GenBank |
| CD29 3D structure databases | | ModBase |
| CD29 Protein protein interaction databases | | STRING |
| CD29 Proteomic databases | | PRIDE |
| CD29 Genome annotation databases | | Ensembl | GeneID | KEGG | UCSC |
| CD29 Organism specific databases | | CTD | MGI |
| CD29 Phylogenomic databases | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| CD29 Gene expression databases | | Bgee | ArrayExpress | Genevestigator |
| CD29 Family and domain databases | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |
