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| Human cd299 (aa 71 – 399) |
| CD299 Swiss Prot | | Q9H2X3 |
| CD299 Protein names | | C-type lectin domain family 4 member M (CD209 antigen-like protein 1) (DC-SIGN-related protein) (DC-SIGNR) (Dendritic cell-specific ICAM-3-grabbing non-integrin 2) (DC-SIGN2) (Liver/lymph node-specific ICAM-3-grabbing non-integrin) (L-SIGN) (CD antigen CD299) |
| CD299 Gene names | | CLEC4M CD209L CD209L1 CD299 |
| Organism | | Human |
| CD299 Entry name | | CLC4M_HUMAN |
| CD299 Codon optimized cDNA Clone |
| CD299 cDNA Cat | | RPV0515 |
| cDNA Tag | | cDNA CD299 contains A 6x histidine tag |
| Condon optimized CD299 cDNA Formulation | | Liquid |
| Condon optimized CD299 cDNA Storage | | Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Condon optimized CD299 cDNA Applications | | Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function. |
| Recombinant CD299 Protein |
| Recombinant CD299 Protein Cat | | PV0515 |
| CD299 Protein Source | | Recombinant protein |
| Recombinant CD299 Protein Applications | | Western Blot, may be used for other applications determined by user |
| Recombinant CD299 Protein Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Recombinant CD299 Protein Activity | | N/A |
| Recombinant protein Tag | | Recombinant CD299 contains A 6x histidine tag |
| Recombinant CD299 Protein Formulation | | Liquid |
| Recombinant CD299 Protein Storage | | Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant CD299 Protein or cDNA | | For pricing and availability, Click Here >>> |
| CD299 SUBUNIT | | SUBUNIT: Homotetramer. Binds to many viral surface glycoproteins such as HIV-1 gp120, HIV-2 gp120, SIV gp120, ebolavirus glycoproteins, HCV E2, and human SARS coronavirus S protein. |
| CD299 Subcellular locations | | SUBCELLULAR LOCATION: Isoform 1: Cell membrane; Single-pass type II membrane protein (Potential). ; SUBCELLULAR LOCATION: Isoform 2: Cell membrane; Single-pass type II membrane protein (Potential). ; SUBCELLULAR LOCATION: Isoform 3: Cell membrane; Single-pass type II membrane protein (Potential). ; SUBCELLULAR LOCATION: Isoform 5: Secreted (Potential). ; SUBCELLULAR LOCATION: Isoform 6: Secreted (Potential). ; SUBCELLULAR LOCATION: Isoform 7: Secreted (Potential). ; |
| | SUBCELLULAR LOCATION: Isoform 10: Secreted (Potential). |
| CD299 FUNCTION According to UniProtKB Swiss Prot | | Probable pathogen-recognition receptor involved in peripheral immune surveillance in liver. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. Probably recognizes in a calcium-dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens, including HIV-1 gp120, HIV-2 gp120, SIV gp120, ebolavirus glycoproteins, HCV E2, and human SARS coronavirus protein S. Is a receptor for ICAM3, probably by binding |
| | to mannose-like carbohydrates. Is presumably a coreceptor for the SARS coronavirus. |
| CD299 Sequence databases | | EMBL | DDBJ | GenBank |
| CD299 3D structure databases | | ModBase |
| CD299 Protein protein interaction databases | | STRING |
| CD299 Proteomic databases | | PRIDE |
| CD299 Genome annotation databases | | Ensembl | GeneID | KEGG | UCSC |
| CD299 Organism specific databases | | CTD | MGI |
| CD299 Phylogenomic databases | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| CD299 Gene expression databases | | Bgee | ArrayExpress | Genevestigator |
| CD299 Family and domain databases | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |
