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| Human cd304 (aa 275 – 424) |
| CD304 Swiss Prot | | O14786 |
| CD304 Protein names | | Neuropilin-1 (Vascular endothelial cell growth factor 165 receptor) (CD antigen CD304) |
| CD304 Gene names | | NRP1 NRP VEGF165R |
| Organism | | Human |
| CD304 Entry name | | NRP1_HUMAN |
| CD304 Codon optimized cDNA Clone |
| CD304 cDNA Cat | | RPV0546 |
| cDNA Tag | | cDNA CD304 contains A 6x histidine tag |
| Condon optimized CD304 cDNA Formulation | | Liquid |
| Condon optimized CD304 cDNA Storage | | Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Condon optimized CD304 cDNA Applications | | Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function. |
| Recombinant CD304 Protein |
| Recombinant CD304 Protein Cat | | PV0546 |
| CD304 Protein Source | | Recombinant protein |
| Recombinant CD304 Protein Applications | | Western Blot, may be used for other applications determined by user |
| Recombinant CD304 Protein Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Recombinant CD304 Protein Activity | | N/A |
| Recombinant protein Tag | | Recombinant CD304 contains A 6x histidine tag |
| Recombinant CD304 Protein Formulation | | Liquid |
| Recombinant CD304 Protein Storage | | Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant CD304 Protein or cDNA | | For pricing and availability, Click Here >>> |
| CD304 SUBUNIT | | SUBUNIT: Homodimer, and heterodimer with NRP2. Binds PLXNB1. |
| CD304 Subcellular locations | | SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein. ; SUBCELLULAR LOCATION: Isoform 2: Secreted. |
| CD304 FUNCTION According to UniProtKB Swiss Prot | | The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. |
| | It may regulate VEGF-induced angiogenesis.; The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells. It may also induce apoptosis by sequestering VEGF-165. May bind as well various members of the semaphorin |
| | family. Its expression has an averse effect on blood vessel number and integrity. |
| CD304 Sequence databases | | EMBL | DDBJ | GenBank |
| CD304 3D structure databases | | ModBase |
| CD304 Protein protein interaction databases | | STRING |
| CD304 Proteomic databases | | PRIDE |
| CD304 Genome annotation databases | | Ensembl | GeneID | KEGG | UCSC |
| CD304 Organism specific databases | | CTD | MGI |
| CD304 Phylogenomic databases | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| CD304 Gene expression databases | | Bgee | ArrayExpress | Genevestigator |
| CD304 Family and domain databases | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |
