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| Human cd113 (aa 58 – 404) |
| CD113 Swiss Prot | | Q9NQS3 |
| CD113 Protein names | | Poliovirus receptor-related protein 3 (CDw113) (Nectin-3) (CD antigen CD113) |
| CD113 Gene names | | PVRL3 PRR3 |
| Organism | | Human |
| CD113 Entry name | | PVRL3_HUMAN |
| CD113 Codon optimized cDNA Clone |
| CD113 cDNA Cat | | RPV0055 |
| cDNA Tag | | cDNA CD113 contains A 6x histidine tag |
| Condon optimized CD113 cDNA Formulation | | Liquid |
| Condon optimized CD113 cDNA Storage | | Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Condon optimized CD113 cDNA Applications | | Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function. |
| Recombinant CD113 Protein |
| Recombinant CD113 Protein Cat | | PV0055 |
| CD113 Protein Source | | Recombinant protein |
| Recombinant CD113 Protein Applications | | Western Blot, may be used for other applications determined by user |
| Recombinant CD113 Protein Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Recombinant CD113 Protein Activity | | N/A |
| Recombinant protein Tag | | Recombinant CD113 contains A 6x histidine tag |
| Recombinant CD113 Protein Formulation | | Liquid |
| Recombinant CD113 Protein Storage | | Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant CD113 Protein or cDNA | | For pricing and availability, Click Here >>> |
| CD113 SUBUNIT | | SUBUNIT: Cis- and trans-homodimer. Can form trans-heterodimers with PVRL1/nectin-1, PVRL2/nectin-2, PVR, IGSF4B/Necl-1 and with IGSF4. Interacts with MLLT4/afadin. Binds with low affinity to TIGIT. |
| CD113 Subcellular locations | | SUBCELLULAR LOCATION: Cell membrane; Single-pass membrane protein (Potential). |
| CD113 FUNCTION According to UniProtKB Swiss Prot | | Plays a role in cell-cell adhesion through heterophilic trans-interactions with nectin-like proteins or nectins, such as trans-interaction with PVRL2/nectin-2 at Sertoli-spermatid junctions. Trans-interaction with PVR induces activation of CDC42 and RAC small G proteins through common signaling molecules such as SRC and RAP1. Also involved in the formation of cell-cell junctions, including adherens junctions and synapses. Induces endocytosis-mediated down-regulation of PVR from the |
| | cell surface, resulting in reduction of cell movement and proliferation. Plays a role in the morphology of the ciliary body. |
| CD113 Sequence databases | | EMBL | DDBJ | GenBank |
| CD113 3D structure databases | | ModBase |
| CD113 Protein protein interaction databases | | STRING |
| CD113 Proteomic databases | | PRIDE |
| CD113 Genome annotation databases | | Ensembl | GeneID | KEGG | UCSC |
| CD113 Organism specific databases | | CTD | MGI |
| CD113 Phylogenomic databases | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| CD113 Gene expression databases | | Bgee | ArrayExpress | Genevestigator |
| CD113 Family and domain databases | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |
