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Human cd314 (aa 73 – 216)
CD314 Swiss Prot
P26718
CD314 Protein names
NKG2-D type II integral membrane protein (Killer cell lectin-like receptor subfamily K member 1) (NK cell receptor D) (NKG2-D-activating NK receptor) (CD antigen CD314)
CD314 Gene names
KLRK1 D12S2489E NKG2D
Organism
Human
CD314 Entry name
NKG2D_HUMAN
CD314 Codon optimized cDNA Clone
CD314 cDNA Cat
RPV0561
cDNA Tag
cDNA CD314 contains A 6x histidine tag
Condon optimized CD314 cDNA Formulation
Liquid
Condon optimized CD314 cDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Condon optimized CD314 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function.
Recombinant CD314 Protein
Recombinant CD314 Protein Cat
PV0561
CD314 Protein Source
Recombinant protein
Recombinant CD314 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant CD314 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant CD314 Protein Activity
N/A
Recombinant protein Tag
Recombinant CD314 contains A 6x histidine tag
Recombinant CD314 Protein Formulation
Liquid
Recombinant CD314 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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CD314 SUBUNIT
SUBUNIT: Homodimer. Interacts with DAP10. The interaction with DAP10 is required for NKG2D cell surface expression.
CD314 Subcellular locations
SUBCELLULAR LOCATION: Membrane; Single-pass type II membrane protein.
CD314 FUNCTION According to UniProtKB Swiss Prot
Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes.
CD314 Sequence databases
EMBL DDBJ GenBank
CD314 3D structure databases
ModBase
CD314 Protein protein interaction databases
STRING
CD314 Proteomic databases
PRIDE
CD314 Genome annotation databases
Ensembl GeneID KEGG UCSC
CD314 Organism specific databases
CTD MGI
CD314 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
CD314 Gene expression databases
Bgee ArrayExpress Genevestigator
CD314 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY