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Human cd316 (aa 28 – 579)
CD316 Swiss Prot
Q969P0
CD316 Protein names
Immunoglobulin superfamily member 8 (IgSF8) (CD81 partner 3) (Glu-Trp-Ile EWI motif-containing protein 2) (EWI-2) (Keratinocytes-associated transmembrane protein 4) (KCT-4) (LIR-D1) (CD antigen CD316)
CD316 Gene names
IGSF8 CD81P3 EWI2 KCT4
Organism
Human
CD316 Entry name
IGSF8_HUMAN
CD316 Codon optimized cDNA Clone
CD316 cDNA Cat
RPV0567
cDNA Tag
cDNA CD316 contains A 6x histidine tag
Condon optimized CD316 cDNA Formulation
Liquid
Condon optimized CD316 cDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Condon optimized CD316 cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function.
Recombinant CD316 Protein
Recombinant CD316 Protein Cat
PV0567
CD316 Protein Source
Recombinant protein
Recombinant CD316 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant CD316 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant CD316 Protein Activity
N/A
Recombinant protein Tag
Recombinant CD316 contains A 6x histidine tag
Recombinant CD316 Protein Formulation
Liquid
Recombinant CD316 Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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CD316 SUBUNIT
SUBUNIT: Interacts directly with CD82, CD81/tetraspanin-28 and CD9/tetraspanin-29. Also interacts with integrin alpha-3/beta-1 and integrin alpha-4/beta-1.
CD316 Subcellular locations
SUBCELLULAR LOCATION: Membrane; Single-pass membrane protein (Potential).
CD316 FUNCTION According to UniProtKB Swiss Prot
May play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. May regulate proliferation and differentiation of keratinocytes. May be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. May also play a role on

integrin-dependent morphology and motility functions. May participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain.
CD316 Sequence databases
EMBL DDBJ GenBank
CD316 3D structure databases
ModBase
CD316 Protein protein interaction databases
STRING
CD316 Proteomic databases
PRIDE
CD316 Genome annotation databases
Ensembl GeneID KEGG UCSC
CD316 Organism specific databases
CTD MGI
CD316 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
CD316 Gene expression databases
Bgee ArrayExpress Genevestigator
CD316 Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY