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| Rat cd321 (aa 27 – 238) |
| CD321 Swiss Prot | | Q9JHY1 |
| CD321 Protein names | | Junctional adhesion molecule A (JAM-A) (Junctional adhesion molecule 1) (JAM-1) (CD antigen CD321) |
| CD321 Gene names | | F11r Jam1 |
| Organism | | Rat |
| CD321 Entry name | | JAM1_RAT |
| CD321 Codon optimized cDNA Clone |
| CD321 cDNA Cat | | RPV0587 |
| cDNA Tag | | cDNA CD321 contains A 6x histidine tag |
| Condon optimized CD321 cDNA Formulation | | Liquid |
| Condon optimized CD321 cDNA Storage | | Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Condon optimized CD321 cDNA Applications | | Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function. |
| Recombinant CD321 Protein |
| Recombinant CD321 Protein Cat | | PV0587 |
| CD321 Protein Source | | Recombinant protein |
| Recombinant CD321 Protein Applications | | Western Blot, may be used for other applications determined by user |
| Recombinant CD321 Protein Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Recombinant CD321 Protein Activity | | N/A |
| Recombinant protein Tag | | Recombinant CD321 contains A 6x histidine tag |
| Recombinant CD321 Protein Formulation | | Liquid |
| Recombinant CD321 Protein Storage | | Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant CD321 Protein or cDNA | | For pricing and availability, Click Here >>> |
| CD321 SUBUNIT | | SUBUNIT: Interacts with the ninth PDZ domain of MPDZ. Interacts with the first PDZ domain of PARD3. The association between PARD3 and PARD6B probably disrupts this interaction. Interacts with the orthoreovirus sigma-1 capsid protein (By similarity). |
| CD321 Subcellular locations | | SUBCELLULAR LOCATION: Cell junction, tight junction (By similarity). Cell membrane; Single-pass type I membrane protein (By similarity). Note=Localized at tight junctions of both epithelial and endothelial cells (By similarity). |
| CD321 FUNCTION According to UniProtKB Swiss Prot | | Seems to plays a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus (By |
| | similarity). |
| CD321 Sequence databases | | EMBL | DDBJ | GenBank |
| CD321 3D structure databases | | ModBase |
| CD321 Protein protein interaction databases | | STRING |
| CD321 Proteomic databases | | PRIDE |
| CD321 Genome annotation databases | | Ensembl | GeneID | KEGG | UCSC |
| CD321 Organism specific databases | | CTD | MGI |
| CD321 Phylogenomic databases | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| CD321 Gene expression databases | | Bgee | ArrayExpress | Genevestigator |
| CD321 Family and domain databases | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |
