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| Mouse cd358 (aa 42 – 349) |
| CD358 Swiss Prot | | Q9EPU5 |
| CD358 Protein names | | Tumor necrosis factor receptor superfamily member 21 (Death receptor 6) (CD antigen CD358) |
| CD358 Gene names | | Tnfrsf21 Dr6 |
| Organism | | Mouse |
| CD358 Entry name | | TNR21_MOUSE |
| CD358 Codon optimized cDNA Clone |
| CD358 cDNA Cat | | RPV0651 |
| cDNA Tag | | cDNA CD358 contains A 6x histidine tag |
| Condon optimized CD358 cDNA Formulation | | Liquid |
| Condon optimized CD358 cDNA Storage | | Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Condon optimized CD358 cDNA Applications | | Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function. |
| Recombinant CD358 Protein |
| Recombinant CD358 Protein Cat | | PV0651 |
| CD358 Protein Source | | Recombinant protein |
| Recombinant CD358 Protein Applications | | Western Blot, may be used for other applications determined by user |
| Recombinant CD358 Protein Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Recombinant CD358 Protein Activity | | N/A |
| Recombinant protein Tag | | Recombinant CD358 contains A 6x histidine tag |
| Recombinant CD358 Protein Formulation | | Liquid |
| Recombinant CD358 Protein Storage | | Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant CD358 Protein or cDNA | | For pricing and availability, Click Here >>> |
| CD358 SUBUNIT | | SUBUNIT: Associates with TRADD (By similarity). Interacts with N-APP. |
| CD358 Subcellular locations | | SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein (Probable). |
| CD358 FUNCTION According to UniProtKB Swiss Prot | | May activate NF-kappa-B and promote apoptosis (By similarity). May activate JNK and be involved in T-cell differentiation. Required for both normal cell body death and axonal pruning. Trophic-factor deprivation triggers the cleavage of surface APP by beta-secretase to release sAPP-beta which is further cleaved to release an N-terminal fragment of APP (N-APP). N-APP binds TNFRSF21 triggering caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via |
| | caspase-6). |
| CD358 Sequence databases | | EMBL | DDBJ | GenBank |
| CD358 3D structure databases | | ModBase |
| CD358 Protein protein interaction databases | | STRING |
| CD358 Proteomic databases | | PRIDE |
| CD358 Genome annotation databases | | Ensembl | GeneID | KEGG | UCSC |
| CD358 Organism specific databases | | CTD | MGI |
| CD358 Phylogenomic databases | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| CD358 Gene expression databases | | Bgee | ArrayExpress | Genevestigator |
| CD358 Family and domain databases | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |
