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| Rat cd41 (aa 32 – 420) |
| CD41 Swiss Prot | | D3ZAC0 |
| CD41 Protein names | | Integrin alpha-IIb (GPalpha IIb) (GPIIb) (Platelet membrane glycoprotein IIb) (CD antigen CD41) [Cleaved into: Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain] |
| CD41 Gene names | | Itga2b |
| Organism | | Rat |
| CD41 Entry name | | D3ZAC0_RAT |
| CD41 Codon optimized cDNA Clone |
| CD41 cDNA Cat | | RPV0695 |
| cDNA Tag | | cDNA CD41 contains A 6x histidine tag |
| Condon optimized CD41 cDNA Formulation | | Liquid |
| Condon optimized CD41 cDNA Storage | | Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Condon optimized CD41 cDNA Applications | | Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function. |
| Recombinant CD41 Protein |
| Recombinant CD41 Protein Cat | | PV0695 |
| CD41 Protein Source | | Recombinant protein |
| Recombinant CD41 Protein Applications | | Western Blot, may be used for other applications determined by user |
| Recombinant CD41 Protein Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Recombinant CD41 Protein Activity | | N/A |
| Recombinant protein Tag | | Recombinant CD41 contains A 6x histidine tag |
| Recombinant CD41 Protein Formulation | | Liquid |
| Recombinant CD41 Protein Storage | | Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant CD41 Protein or cDNA | | For pricing and availability, Click Here >>> |
| CD41 SUBUNIT | | - |
| CD41 Subcellular locations | | - |
| CD41 FUNCTION According to UniProtKB Swiss Prot | | Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial |
| | cell surface. |
| CD41 Sequence databases | | EMBL | DDBJ | GenBank |
| CD41 3D structure databases | | ModBase |
| CD41 Protein protein interaction databases | | STRING |
| CD41 Proteomic databases | | PRIDE |
| CD41 Genome annotation databases | | Ensembl | GeneID | KEGG | UCSC |
| CD41 Organism specific databases | | CTD | MGI |
| CD41 Phylogenomic databases | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| CD41 Gene expression databases | | Bgee | ArrayExpress | Genevestigator |
| CD41 Family and domain databases | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |