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| Rat cd45 (aa 24 – 546) |
| CD45 Swiss Prot | | P04157 |
| CD45 Protein names | | Receptor-type tyrosine-protein phosphatase C (EC 3.1.3.48) (Leukocyte common antigen) (L-CA) (T200) (CD antigen CD45) |
| CD45 Gene names | | Ptprc |
| Organism | | Rat |
| CD45 Entry name | | PTPRC_RAT |
| CD45 Codon optimized cDNA Clone |
| CD45 cDNA Cat | | RPV0710 |
| cDNA Tag | | cDNA CD45 contains A 6x histidine tag |
| Condon optimized CD45 cDNA Formulation | | Liquid |
| Condon optimized CD45 cDNA Storage | | Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Condon optimized CD45 cDNA Applications | | Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function. |
| Recombinant CD45 Protein |
| Recombinant CD45 Protein Cat | | PV0710 |
| CD45 Protein Source | | Recombinant protein |
| Recombinant CD45 Protein Applications | | Western Blot, may be used for other applications determined by user |
| Recombinant CD45 Protein Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Recombinant CD45 Protein Activity | | N/A |
| Recombinant protein Tag | | Recombinant CD45 contains A 6x histidine tag |
| Recombinant CD45 Protein Formulation | | Liquid |
| Recombinant CD45 Protein Storage | | Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant CD45 Protein or cDNA | | For pricing and availability, Click Here >>> |
| CD45 SUBUNIT | | SUBUNIT: Interacts with SKAP1. Interacts with DPP4; the interaction is enhanced in a interleukin-12-dependent manner in activated lymphocytes. Binds GANAB and PRKCSH (By similarity). |
| CD45 Subcellular locations | | SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein (By similarity). Membrane raft (By similarity). Note=Colocalized with DPP4 in membrane rafts (By similarity). |
| CD45 FUNCTION According to UniProtKB Swiss Prot | | Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN (By similarity). |
| CD45 Sequence databases | | EMBL | DDBJ | GenBank |
| CD45 3D structure databases | | ModBase |
| CD45 Protein protein interaction databases | | STRING |
| CD45 Proteomic databases | | PRIDE |
| CD45 Genome annotation databases | | Ensembl | GeneID | KEGG | UCSC |
| CD45 Organism specific databases | | CTD | MGI |
| CD45 Phylogenomic databases | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| CD45 Gene expression databases | | Bgee | ArrayExpress | Genevestigator |
| CD45 Family and domain databases | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |
