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| Mouse cd49d (aa 41 – 440) |
| CD49d Swiss Prot | | Q00651 |
| CD49d Protein names | | Integrin alpha-4 (CD49 antigen-like family member D) (Integrin alpha-IV) (Lymphocyte Peyer patch adhesion molecules subunit alpha) (LPAM subunit alpha) (VLA-4 subunit alpha) (CD antigen CD49d) |
| CD49d Gene names | | Itga4 |
| Organism | | Mouse |
| CD49d Entry name | | ITA4_MOUSE |
| CD49d Codon optimized cDNA Clone |
| CD49d cDNA Cat | | RPV0729 |
| cDNA Tag | | cDNA CD49d contains A 6x histidine tag |
| Condon optimized CD49d cDNA Formulation | | Liquid |
| Condon optimized CD49d cDNA Storage | | Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Condon optimized CD49d cDNA Applications | | Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function. |
| Recombinant CD49d Protein |
| Recombinant CD49d Protein Cat | | PV0729 |
| CD49d Protein Source | | Recombinant protein |
| Recombinant CD49d Protein Applications | | Western Blot, may be used for other applications determined by user |
| Recombinant CD49d Protein Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Recombinant CD49d Protein Activity | | N/A |
| Recombinant protein Tag | | Recombinant CD49d contains A 6x histidine tag |
| Recombinant CD49d Protein Formulation | | Liquid |
| Recombinant CD49d Protein Storage | | Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant CD49d Protein or cDNA | | For pricing and availability, Click Here >>> |
| CD49d SUBUNIT | | SUBUNIT: Heterodimer of an alpha and a beta subunit. The alpha subunit can sometimes be cleaved into two non-covalently associated fragments. Alpha-4 associates with either beta-1 or beta-7. Alpha-4 interacts with PXN, LPXN, and TGFB1I1/HIC5. Interacts with CSPG4 through CSPG4 chondroitin sulfate glycosaminoglycan (By similarity). |
| CD49d Subcellular locations | | SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. |
| CD49d FUNCTION According to UniProtKB Swiss Prot | | Integrins alpha-4/beta-1 (VLA-4 or LPAM-2) and alpha-4/beta-7 (LPAM-1) are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1. On activated endothelial cells integrin VLA-4 triggers homotypic |
| | aggregation for most VLA-4-positive leukocyte cell lines. It may also participate in cytolytic T-cell interactions with target cells. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. Mice homozygous for a null mutation of the alpha-4 |
| | subunit gene die by day E11-E14 from detachment and rupture of the epicardium and coronary arteries. |
| CD49d Sequence databases | | EMBL | DDBJ | GenBank |
| CD49d 3D structure databases | | ModBase |
| CD49d Protein protein interaction databases | | STRING |
| CD49d Proteomic databases | | PRIDE |
| CD49d Genome annotation databases | | Ensembl | GeneID | KEGG | UCSC |
| CD49d Organism specific databases | | CTD | MGI |
| CD49d Phylogenomic databases | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| CD49d Gene expression databases | | Bgee | ArrayExpress | Genevestigator |
| CD49d Family and domain databases | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |
