|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Copyright
Bioclone Inc All rights Reserved
|
|
|
||||||||||||||||||||||||||||||||||
|
|||||||||||||
| Human cd49e (aa 42 – 440) |
| CD49e Swiss Prot | | P08648 |
| CD49e Protein names | | Integrin alpha-5 (CD49 antigen-like family member E) (Fibronectin receptor subunit alpha) (Integrin alpha-F) (VLA-5) (CD antigen CD49e) [Cleaved into: Integrin alpha-5 heavy chain; Integrin alpha-5 light chain] |
| CD49e Gene names | | ITGA5 FNRA |
| Organism | | Human |
| CD49e Entry name | | ITA5_HUMAN |
| CD49e Codon optimized cDNA Clone |
| CD49e cDNA Cat | | RPV0730 |
| cDNA Tag | | cDNA CD49e contains A 6x histidine tag |
| Condon optimized CD49e cDNA Formulation | | Liquid |
| Condon optimized CD49e cDNA Storage | | Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Condon optimized CD49e cDNA Applications | | Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function. |
| Recombinant CD49e Protein |
| Recombinant CD49e Protein Cat | | PV0730 |
| CD49e Protein Source | | Recombinant protein |
| Recombinant CD49e Protein Applications | | Western Blot, may be used for other applications determined by user |
| Recombinant CD49e Protein Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Recombinant CD49e Protein Activity | | N/A |
| Recombinant protein Tag | | Recombinant CD49e contains A 6x histidine tag |
| Recombinant CD49e Protein Formulation | | Liquid |
| Recombinant CD49e Protein Storage | | Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant CD49e Protein or cDNA | | For pricing and availability, Click Here >>> |
| CD49e SUBUNIT | | SUBUNIT: Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chain linked by a disulfide bond. Alpha-5 associates with beta-1. Interacts with HPS5 and NISCH. Interacts with RAB21 and COMP. Interacts with HIV-1 Tat. |
| CD49e Subcellular locations | | SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. |
| CD49e FUNCTION According to UniProtKB Swiss Prot | | Integrin alpha-5/beta-1 is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. |
| CD49e Sequence databases | | EMBL | DDBJ | GenBank |
| CD49e 3D structure databases | | ModBase |
| CD49e Protein protein interaction databases | | STRING |
| CD49e Proteomic databases | | PRIDE |
| CD49e Genome annotation databases | | Ensembl | GeneID | KEGG | UCSC |
| CD49e Organism specific databases | | CTD | MGI |
| CD49e Phylogenomic databases | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| CD49e Gene expression databases | | Bgee | ArrayExpress | Genevestigator |
| CD49e Family and domain databases | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |
