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Human MBP (aa 1-304)

MBP Swiss Prot#

P02686

MBP Protein names

Myelin basic protein (MBP) (Myelin A1 protein) (Myelin membrane

encephalitogenic protein)

MBP Gene names

MBP

Organism

Human

MBP Entry name

MBP_HUMAN

MBP Codon optimized cDNA Clone

MBP CDNA Cat#

RPU0075

cDNA Tag

cDNA MBP Contains A 6x histidine tag

Condon optimized MBP CDNA Formulation

Liquid

Condon optimized MBP CDNA Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

Condon optimized MBP cDNA Applications

Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant MBP Protein

Recombinant MBP Protein Cat#

PU0075

MBP Protein Source

Recombinant protein.

Recombinant MBP Protein Applications

Western Blot, may be used for other applications determined by user

Recombinant MBP Protein Purity

>90%, as determined by SDS-PAGE under reducing conditions

Recombinant MBP Protein Activity

N/A

Recombinant protein Tag

Recombinant MBP contains A 6x histidine tag

Recombinant MBP Protein Formulation

Liquid

Recombinant MBP Protein Storage

Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

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MBP Protein family

Myelin basic protein family

MBP Subcellular locations

Myelin membrane; Peripheral membrane protein; Cytoplasmic side.

MBP FUNCTION (According to UniProtKB/Swiss Prot)

FUNCTION: The classic group of MBP isoforms (isoform 4-isoform 14) are

with PLP the most abundant protein components of the myelin membrane in

the CNS. They have a role in both its formation and stabilization. The smaller

isoforms might have an important role in remyelination of denuded axons in

multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-

isoform 3/Golli-MBPs) may preferentially have a role in the early developing

brain long before myelination, maybe as components of transcriptional

complexes, and may also be involved in signaling pathways in T-cells and

neural cells. Differential splicing events combined with optional post-

translational modifications give a wide spectrum of isomers, with each of

them potentially having a specialized function. Induces T-cell proliferation.

MBP Sequence databases

EMBL

DDBJ

GenBank

MBP 3D structure databases

ModBase

MBP Protein-protein interaction databases

STRING

MBP Proteomic databases

PRIDE

MBP Genome annotation databases

Ensembl

GeneID

KEGG

UCSC

MBP Organism specific databases

CTD

MGI

MBP Phylogenomic databases

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

MBP Gene expression databases

Bgee

ArrayExpress

Genevestigator

MBP Family and domain databases

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY