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| Mouse cd61 (aa 134 – 376) |
| CD61 Swiss Prot | | O54890 |
| CD61 Protein names | | Integrin beta-3 (Platelet membrane glycoprotein IIIa) (GPIIIa) (CD antigen CD61) |
| CD61 Gene names | | Itgb3 |
| Organism | | Mouse |
| CD61 Entry name | | ITB3_MOUSE |
| CD61 Codon optimized cDNA Clone |
| CD61 cDNA Cat | | RPV0767 |
| cDNA Tag | | cDNA CD61 contains A 6x histidine tag |
| Condon optimized CD61 cDNA Formulation | | Liquid |
| Condon optimized CD61 cDNA Storage | | Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Condon optimized CD61 cDNA Applications | | Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function. |
| Recombinant CD61 Protein |
| Recombinant CD61 Protein Cat | | PV0767 |
| CD61 Protein Source | | Recombinant protein |
| Recombinant CD61 Protein Applications | | Western Blot, may be used for other applications determined by user |
| Recombinant CD61 Protein Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Recombinant CD61 Protein Activity | | N/A |
| Recombinant protein Tag | | Recombinant CD61 contains A 6x histidine tag |
| Recombinant CD61 Protein Formulation | | Liquid |
| Recombinant CD61 Protein Storage | | Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant CD61 Protein or cDNA | | For pricing and availability, Click Here >>> |
| CD61 SUBUNIT | | SUBUNIT: Heterodimer of an alpha and a beta subunit. Beta-3 associates with either alpha-IIB or alpha-V. Interacts with FLNB and COMP. Interacts with PDIA6 following platelet stimulation (By similarity). |
| CD61 Subcellular locations | | SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. |
| CD61 FUNCTION According to UniProtKB Swiss Prot | | Integrin alpha-V/beta-3 is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha-IIB/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. Integrins alpha-IIB/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands. Integrin alpha-IIB/beta-3 recognizes the sequence H-H-L-G- |
| | G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIB/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs |
| | ruptured endothelial surface. |
| CD61 Sequence databases | | EMBL | DDBJ | GenBank |
| CD61 3D structure databases | | ModBase |
| CD61 Protein protein interaction databases | | STRING |
| CD61 Proteomic databases | | PRIDE |
| CD61 Genome annotation databases | | Ensembl | GeneID | KEGG | UCSC |
| CD61 Organism specific databases | | CTD | MGI |
| CD61 Phylogenomic databases | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| CD61 Gene expression databases | | Bgee | ArrayExpress | Genevestigator |
| CD61 Family and domain databases | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |
