|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Copyright
Bioclone Inc All rights Reserved
|
|
|
||||||||||||||||||||||||||||||||||
|
|||||||||||||
| Human cd11b (aa 17 – 417) |
| CD11b Swiss Prot | | P11215 |
| CD11b Protein names | | Integrin alpha-M (CD11 antigen-like family member B) (CR-3 alpha chain) (Cell surface glycoprotein MAC-1 subunit alpha) (Leukocyte adhesion receptor MO1) (Neutrophil adherence receptor) (CD antigen CD11b) |
| CD11b Gene names | | ITGAM CD11B CR3A |
| Organism | | Human |
| CD11b Entry name | | ITAM_HUMAN |
| CD11b Codon optimized cDNA Clone |
| CD11b cDNA Cat | | RPV0078 |
| cDNA Tag | | cDNA CD11b contains A 6x histidine tag |
| Condon optimized CD11b cDNA Formulation | | Liquid |
| Condon optimized CD11b cDNA Storage | | Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Condon optimized CD11b cDNA Applications | | Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function. |
| Recombinant CD11b Protein |
| Recombinant CD11b Protein Cat | | PV0078 |
| CD11b Protein Source | | Recombinant protein |
| Recombinant CD11b Protein Applications | | Western Blot, may be used for other applications determined by user |
| Recombinant CD11b Protein Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Recombinant CD11b Protein Activity | | N/A |
| Recombinant protein Tag | | Recombinant CD11b contains A 6x histidine tag |
| Recombinant CD11b Protein Formulation | | Liquid |
| Recombinant CD11b Protein Storage | | Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant CD11b Protein or cDNA | | For pricing and availability, Click Here >>> |
| CD11b SUBUNIT | | SUBUNIT: Heterodimer of an alpha and a beta subunit. Alpha-M associates with beta-2. Interacts with JAM3. |
| CD11b Subcellular locations | | SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. |
| CD11b FUNCTION According to UniProtKB Swiss Prot | | Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain. |
| CD11b Sequence databases | | EMBL | DDBJ | GenBank |
| CD11b 3D structure databases | | ModBase |
| CD11b Protein protein interaction databases | | STRING |
| CD11b Proteomic databases | | PRIDE |
| CD11b Genome annotation databases | | Ensembl | GeneID | KEGG | UCSC |
| CD11b Organism specific databases | | CTD | MGI |
| CD11b Phylogenomic databases | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| CD11b Gene expression databases | | Bgee | ArrayExpress | Genevestigator |
| CD11b Family and domain databases | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |
