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Human NDN (aa 1-321)

NDN Swiss Prot#

Q99608

NDN Protein names

Necdin

NDN Gene names

NDN

Organism

Human

NDN Entry name

NECD_HUMAN

NDN Codon optimized cDNA Clone

NDN CDNA Cat#

RPU0078

cDNA Tag

cDNA NDN Contains A 6x histidine tag

Condon optimized NDN CDNA Formulation

Liquid

Condon optimized NDN CDNA Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

Condon optimized NDN cDNA Applications

Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant NDN Protein

Recombinant NDN Protein Cat#

PU0078

NDN Protein Source

Recombinant protein.

Recombinant NDN Protein Applications

Western Blot, may be used for other applications determined by user

Recombinant NDN Protein Purity

>90%, as determined by SDS-PAGE under reducing conditions

Recombinant NDN Protein Activity

N/A

Recombinant protein Tag

Recombinant NDN contains A 6x histidine tag

Recombinant NDN Protein Formulation

Liquid

Recombinant NDN Protein Storage

Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

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NDN Protein family

NDN Subcellular locations

Perikaryon. Nucleus.

NDN FUNCTION (According to UniProtKB/Swiss Prot)

FUNCTION: Growth suppressor that facilitates the entry of the cell into cell

cycle arrest. Functionally similar to the retinoblastoma protein it binds to

and represses the activity of cell-cycle-promoting proteins such as SV40

large T antigen, adenovirus E1A, and the transcription factor E2F. Necdin

also interacts with p53 and works in an additive manner to inhibit cell

growth. Functions also as transcription factor and binds directly to specific

guanosine-rich DNA sequences (By similarity).

NDN Sequence databases

EMBL

DDBJ

GenBank

NDN 3D structure databases

ModBase

NDN Protein-protein interaction databases

STRING

NDN Proteomic databases

PRIDE

NDN Genome annotation databases

Ensembl

GeneID

KEGG

UCSC

NDN Organism specific databases

CTD

MGI

NDN Phylogenomic databases

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

NDN Gene expression databases

Bgee

ArrayExpress

Genevestigator

NDN Family and domain databases

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY