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Human cd121a (aa 18 – 336)
CD121a Swiss Prot
P14778
CD121a Protein names
Interleukin-1 receptor type 1 (IL-1R-1) (IL-1RT-1) (IL-1RT1) (CD121 antigen-like family member A) (Interleukin-1 receptor alpha) (IL-1R-alpha) (Interleukin-1 receptor type I) (p80) (CD antigen CD121a)
CD121a Gene names
IL1R1 IL1R IL1RA IL1RT1
Organism
Human
CD121a Entry name
IL1R1_HUMAN
CD121a Codon optimized cDNA Clone
CD121a cDNA Cat
RPV0083
cDNA Tag
cDNA CD121a contains A 6x histidine tag
Condon optimized CD121a cDNA Formulation
Liquid
Condon optimized CD121a cDNA Storage
Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Condon optimized CD121a cDNA Applications
Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function.
Recombinant CD121a Protein
Recombinant CD121a Protein Cat
PV0083
CD121a Protein Source
Recombinant protein
Recombinant CD121a Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant CD121a Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant CD121a Protein Activity
N/A
Recombinant protein Tag
Recombinant CD121a contains A 6x histidine tag
Recombinant CD121a Protein Formulation
Liquid
Recombinant CD121a Protein Storage
Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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CD121a SUBUNIT
SUBUNIT: Binds IL1RAP.
CD121a Subcellular locations
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
CD121a FUNCTION According to UniProtKB Swiss Prot
Receptor for interleukin-1 alpha (IL-1A), beta (IL-1B), and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappa-B. Signaling involves formation of a ternary complex containing IL1RAP, TOLLIP, MYD88, and IRAK1 or IRAK2.
CD121a Sequence databases
EMBL DDBJ GenBank
CD121a 3D structure databases
ModBase
CD121a Protein protein interaction databases
STRING
CD121a Proteomic databases
PRIDE
CD121a Genome annotation databases
Ensembl GeneID KEGG UCSC
CD121a Organism specific databases
CTD MGI
CD121a Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
CD121a Gene expression databases
Bgee ArrayExpress Genevestigator
CD121a Family and domain databases
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY