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| Human CD85j (aa 24 – 461) |
| CD85j Swiss Prot | | Q8NHL6 |
| CD85j Protein names | | Leukocyte immunoglobulin-like receptor subfamily B member 1 (LIR-1) (Leukocyte immunoglobulin-like receptor 1) (CD85 antigen-like family member J) (Immunoglobulin-like transcript 2) (ILT-2) (Monocyte/macrophage immunoglobulin-like receptor 7) (MIR-7) (CD antigen CD85j) |
| CD85j Gene names | | LILRB1 ILT2 LIR1 MIR7 |
| Organism | | Human |
| CD85j Entry name | | LIRB1_HUMAN |
| CD85j Codon optimized cDNA Clone |
| CD85j cDNA Cat | | RPV0849 |
| cDNA Tag | | cDNA CD85j contains A 6x histidine tag |
| Condon optimized CD85j cDNA Formulation | | Liquid |
| Condon optimized CD85j cDNA Storage | | Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Condon optimized CD85j cDNA Applications | | Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function. |
| Recombinant CD85j Protein |
| Recombinant CD85j Protein Cat | | PV0849 |
| CD85j Protein Source | | Recombinant protein |
| Recombinant CD85j Protein Applications | | Western Blot, may be used for other applications determined by user |
| Recombinant CD85j Protein Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Recombinant CD85j Protein Activity | | N/A |
| Recombinant protein Tag | | Recombinant CD85j contains A 6x histidine tag |
| Recombinant CD85j Protein Formulation | | Liquid |
| Recombinant CD85j Protein Storage | | Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant CD85j Protein or cDNA | | For pricing and availability, Click Here >>> |
| CD85j SUBUNIT | | SUBUNIT: Binds PTPN6 when phosphorylated. Binds FCER1A and FCGR1A. |
| CD85j Subcellular locations | | SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. |
| CD85j FUNCTION According to UniProtKB Swiss Prot | | Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Receptor for H301/UL18, a human cytomegalovirus class I MHC homolog. Ligand binding results in inhibitory signals and down-regulation of the immune response. Engagement of LILRB1 present on natural killer cells or T-cells by class I MHC molecules protects the target cells from lysis. Interaction with HLA-B or HLA-E leads to inhibition of the signal triggered by FCER1A and |
| | inhibits serotonin release. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions. |
| CD85j Sequence databases | | EMBL | DDBJ | GenBank |
| CD85j 3D structure databases | | ModBase |
| CD85j Protein protein interaction databases | | STRING |
| CD85j Proteomic databases | | PRIDE |
| CD85j Genome annotation databases | | Ensembl | GeneID | KEGG | UCSC |
| CD85j Organism specific databases | | CTD | MGI |
| CD85j Phylogenomic databases | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| CD85j Gene expression databases | | Bgee | ArrayExpress | Genevestigator |
| CD85j Family and domain databases | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |
