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| Human CD85k (aa 22 – 259) |
| CD85k Swiss Prot | | Q8NHJ6 |
| CD85k Protein names | | Leukocyte immunoglobulin-like receptor subfamily B member 4 (CD85 antigen-like family member K) (Immunoglobulin-like transcript 3) (ILT-3) (Leukocyte immunoglobulin-like receptor 5) (LIR-5) (Monocyte inhibitory receptor HM18) (CD antigen CD85k) |
| CD85k Gene names | | LILRB4 ILT3 LIR5 |
| Organism | | Human |
| CD85k Entry name | | LIRB4_HUMAN |
| CD85k Codon optimized cDNA Clone |
| CD85k cDNA Cat | | RPV0850 |
| cDNA Tag | | cDNA CD85k contains A 6x histidine tag |
| Condon optimized CD85k cDNA Formulation | | Liquid |
| Condon optimized CD85k cDNA Storage | | Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Condon optimized CD85k cDNA Applications | | Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function. |
| Recombinant CD85k Protein |
| Recombinant CD85k Protein Cat | | PV0850 |
| CD85k Protein Source | | Recombinant protein |
| Recombinant CD85k Protein Applications | | Western Blot, may be used for other applications determined by user |
| Recombinant CD85k Protein Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Recombinant CD85k Protein Activity | | N/A |
| Recombinant protein Tag | | Recombinant CD85k contains A 6x histidine tag |
| Recombinant CD85k Protein Formulation | | Liquid |
| Recombinant CD85k Protein Storage | | Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant CD85k Protein or cDNA | | For pricing and availability, Click Here >>> |
| CD85k SUBUNIT | | SUBUNIT: Binds PTPN6 when phosphorylated. |
| CD85k Subcellular locations | | SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein. Note=Ligand binding leads to internalization and translocation to an antigen-processing compartment. |
| CD85k FUNCTION According to UniProtKB Swiss Prot | | Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Involved in the down-regulation of the immune response and the development of tolerance, e.g. towards transplants. Interferes with TNFRSF5-signaling and NF-kappa-B up-regulation. Inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions. |
| CD85k Sequence databases | | EMBL | DDBJ | GenBank |
| CD85k 3D structure databases | | ModBase |
| CD85k Protein protein interaction databases | | STRING |
| CD85k Proteomic databases | | PRIDE |
| CD85k Genome annotation databases | | Ensembl | GeneID | KEGG | UCSC |
| CD85k Organism specific databases | | CTD | MGI |
| CD85k Phylogenomic databases | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| CD85k Gene expression databases | | Bgee | ArrayExpress | Genevestigator |
| CD85k Family and domain databases | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |
