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| Human CD86 (aa 24 – 247) |
| CD86 Swiss Prot | | P42081 |
| CD86 Protein names | | T-lymphocyte activation antigen CD86 (Activation B7-2 antigen) (B70) (BU63) (CTLA-4 counter-receptor B7.2) (FUN-1) (CD antigen CD86) |
| CD86 Gene names | | CD86 CD28LG2 |
| Organism | | Human |
| CD86 Entry name | | CD86_HUMAN |
| CD86 Codon optimized cDNA Clone |
| CD86 cDNA Cat | | RPV0852 |
| cDNA Tag | | cDNA CD86 contains A 6x histidine tag |
| Condon optimized CD86 cDNA Formulation | | Liquid |
| Condon optimized CD86 cDNA Storage | | Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Condon optimized CD86 cDNA Applications | | Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function. |
| Recombinant CD86 Protein |
| Recombinant CD86 Protein Cat | | PV0852 |
| CD86 Protein Source | | Recombinant protein |
| Recombinant CD86 Protein Applications | | Western Blot, may be used for other applications determined by user |
| Recombinant CD86 Protein Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Recombinant CD86 Protein Activity | | N/A |
| Recombinant protein Tag | | Recombinant CD86 contains A 6x histidine tag |
| Recombinant CD86 Protein Formulation | | Liquid |
| Recombinant CD86 Protein Storage | | Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant CD86 Protein or cDNA | | For pricing and availability, Click Here >>> |
| CD86 SUBUNIT | | SUBUNIT: Homodimer. Interacts with MARCH8. Interacts with human herpesvirus 8 MIR2 protein (Probable). Interacts with adenovirus subgroup B fiber proteins and acts as a receptor for these viruses. |
| CD86 Subcellular locations | | SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein. |
| CD86 FUNCTION According to UniProtKB Swiss Prot | | Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation. |
| CD86 Sequence databases | | EMBL | DDBJ | GenBank |
| CD86 3D structure databases | | ModBase |
| CD86 Protein protein interaction databases | | STRING |
| CD86 Proteomic databases | | PRIDE |
| CD86 Genome annotation databases | | Ensembl | GeneID | KEGG | UCSC |
| CD86 Organism specific databases | | CTD | MGI |
| CD86 Phylogenomic databases | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| CD86 Gene expression databases | | Bgee | ArrayExpress | Genevestigator |
| CD86 Family and domain databases | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |
