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| Rat CD95 (aa 22 – 171) |
| CD95 Swiss Prot | | Q63199 |
| CD95 Protein names | | Tumor necrosis factor receptor superfamily member 6 (Apo-1 antigen) (Apoptosis-mediating surface antigen FAS) (FASLG receptor) (CD antigen CD95) |
| CD95 Gene names | | Fas Apt1 Tnfrsf6 |
| Organism | | Rat |
| CD95 Entry name | | TNR6_RAT |
| CD95 Codon optimized cDNA Clone |
| CD95 cDNA Cat | | RPV0888 |
| cDNA Tag | | cDNA CD95 contains A 6x histidine tag |
| Condon optimized CD95 cDNA Formulation | | Liquid |
| Condon optimized CD95 cDNA Storage | | Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Condon optimized CD95 cDNA Applications | | Applications: 1. Codon-optimized cDNA sequence designed for recombinant protein production in both E.coli and Mammalian cell. The cDNA has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss of function. |
| Recombinant CD95 Protein |
| Recombinant CD95 Protein Cat | | PV0888 |
| CD95 Protein Source | | Recombinant protein |
| Recombinant CD95 Protein Applications | | Western Blot, may be used for other applications determined by user |
| Recombinant CD95 Protein Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| Recombinant CD95 Protein Activity | | N/A |
| Recombinant protein Tag | | Recombinant CD95 contains A 6x histidine tag |
| Recombinant CD95 Protein Formulation | | Liquid |
| Recombinant CD95 Protein Storage | | Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant CD95 Protein or cDNA | | For pricing and availability, Click Here >>> |
| CD95 SUBUNIT | | SUBUNIT: Binds DAXX and RIPK1. Interacts with HIPK3. Part of a complex containing HIPK3 and FADD. Interacts with BRE and FEM1B (By similarity). Interacts with FADD (By similarity). |
| CD95 Subcellular locations | | SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. |
| CD95 FUNCTION According to UniProtKB Swiss Prot | | Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both (By similarity). |
| CD95 Sequence databases | | EMBL | DDBJ | GenBank |
| CD95 3D structure databases | | ModBase |
| CD95 Protein protein interaction databases | | STRING |
| CD95 Proteomic databases | | PRIDE |
| CD95 Genome annotation databases | | Ensembl | GeneID | KEGG | UCSC |
| CD95 Organism specific databases | | CTD | MGI |
| CD95 Phylogenomic databases | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| CD95 Gene expression databases | | Bgee | ArrayExpress | Genevestigator |
| CD95 Family and domain databases | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |
