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HUMAN TRAF4 (aa 1-470 )
TRAF4 Swiss-Prot #
Q9BUZ4
TRAF4 Protein names
TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf

domains protein 1) (Metastatic lymph node gene 62 protein) (MLN 62) (RING finger protein

83)
TRAF4 Gene names
TRAF4 CART1 MLN62 RNF83
Organism
Homo sapiens (Human)
TRAF4 Entry name
TRAF4_HUMAN

TRAF4 Codon-optimized cDNA Clone
TRAF4 CDNA Cat#
RPY1125
Tag
cDNA TRAF4 contains A 6x histidine tag
Condon optimized TRAF4 cDNA Formulation
Liquid
Condon optimized TRAF4 cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized TRAF4 cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag.

2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant TRAF4 Protein
Recombinant TRAF4 Protein Cat#
PY1125
TRAF4 Protein Source
Recombinant protein
Recombinant TRAF4 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant TRAF4 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant TRAF4 Protein Activity
N/A
Tag
Recombinant TRAF4 contains A 6x histidine tag
Recombinant TRAF4 protein Formulation
Liquid
Recombinant TRAF4 protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant TRAF4 Protein or cDNA
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TRAF4 Protein family
TNF receptor-associated factor family, B subfamily
TRAF4 Subcellular locations
Cytoplasm. Nucleus. Cytoplasm > perinuclear region. Cell junction > tight junction. Cell membrane;

Peripheral membrane protein; Cytoplasmic side. Cytoplasm > cytoskeleton.
TRAF4 FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: Adapter protein and signal transducer that links members of the tumor

necrosis factor receptor (TNFR) family to different signaling pathways. Plays a

role in the activation of NF-kappa-B and JNK, and in the regulation of cell survival

and apoptosis. Regulates activation of NF-kappa-B in response to signaling

through Toll-like receptors. Required for normal skeleton development, and for

normal development of the respiratory tract (By similarity). Required for activation of

RPS6KB1 in response to TNF signaling. Modulates TRAF6 functions.
TRAF4 Sequence databases
EMBL DDBJ GenBank
TRAF4 3D structure databases
ModBase
TRAF4 Protein-protein interaction databases
STRING
TRAF4 Proteomic databases
PRIDE
TRAF4 Genome annotation databases
Ensembl GeneID KEGG UCSC
TRAF4 Organism-specific databases
CTD MGI
TRAF4 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
TRAF4 Gene expression databases
Bgee ArrayExpress Genevestigator
TRAF4 Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.