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RAT Katna1 (aa 1-491 )
Katna1 Swiss-Prot #
Q6E0V2
Katna1 Protein names
Katanin p60 ATPase-containing subunit A1 (Katanin p60 subunit A1) (EC 3.6.4.3) (p60

katanin)
Katna1 Gene names
Katna1
Organism
Rattus norvegicus (Rat)
Katna1 Entry name
KTNA1_RAT

Katna1 Codon-optimized cDNA Clone
Katna1 CDNA Cat#
RPY1190
Tag
cDNA Katna1 contains A 6x histidine tag
Condon optimized Katna1 cDNA Formulation
Liquid
Condon optimized Katna1 cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized Katna1 cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag. 2.

May be used as RNAi assistance to restore the loss-of-function.

Recombinant Katna1 Protein
Recombinant Katna1 Protein Cat#
PY1190
Katna1 Protein Source
Recombinant protein
Recombinant Katna1 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Katna1 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Katna1 Protein Activity
N/A
Tag
Recombinant Katna1 contains A 6x histidine tag
Recombinant Katna1 protein Formulation
Liquid
Recombinant Katna1 protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant Katna1 Protein or cDNA
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Katna1 Protein family
AAA ATPase family
Katna1 Subcellular locations
Cytoplasm. Cytoplasm > cytoskeleton > centrosome. Cytoplasm > cytoskeleton > spindle pole.
Katna1 FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: Severs microtubules in vitro in an ATP-dependent manner. This

activity may promote rapid reorganization of cellular microtubule arrays, such as

that seen during disassembly of interphase microtubules at the G2-M transition.

May also be required for microtubule release from the centrosome after nucleation.

In mitotic spindles this could allow depolymerization of the microtubule end proximal

to the centrosome, and subsequent poleward microtubule flux. In neurons,

microtubule release within the cell body allows their subsequent transport into

neuronal processes by microtubule dependent motor proteins. This transport is

required for axonal growth (By similarity).
Katna1 Sequence databases
EMBL DDBJ GenBank
Katna1 3D structure databases
ModBase
Katna1 Protein-protein interaction databases
STRING
Katna1 Proteomic databases
PRIDE
Katna1 Genome annotation databases
Ensembl GeneID KEGG UCSC
Katna1 Organism-specific databases
CTD MGI
Katna1 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
Katna1 Gene expression databases
Bgee ArrayExpress Genevestigator
Katna1 Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.