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HUMAN TCHP (aa 1-498 )
TCHP Swiss-Prot #
Q9BT92
TCHP Protein names
Trichoplein keratin filament-binding protein (Protein TCHP) (Mitochondrial protein with

oncostatic activity) (Mitostatin) (Tumor suppressor protein)
TCHP Gene names
TCHP
Organism
Homo sapiens (Human)
TCHP Entry name
TCHP_HUMAN

TCHP Codon-optimized cDNA Clone
TCHP CDNA Cat#
RPY1214
Tag
cDNA TCHP contains A 6x histidine tag
Condon optimized TCHP cDNA Formulation
Liquid
Condon optimized TCHP cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized TCHP cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag. 2.

May be used as RNAi assistance to restore the loss-of-function.

Recombinant TCHP Protein
Recombinant TCHP Protein Cat#
PY1214
TCHP Protein Source
Recombinant protein
Recombinant TCHP Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant TCHP Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant TCHP Protein Activity
N/A
Tag
Recombinant TCHP contains A 6x histidine tag
Recombinant TCHP protein Formulation
Liquid
Recombinant TCHP protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant TCHP Protein or cDNA
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TCHP Protein family
TCHP family
TCHP Subcellular locations
Cytoplasm > cytoskeleton. Cytoplasm. Cell membrane. Mitochondrion.
TCHP FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: Tumor suppressor which has the ability to inhibit cell growth and be

pro-apoptotic during cell stress. Inhibits cell growth in bladder and prostate cancer

cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. May act as a

'capping' or 'branching' protein for keratin filaments in the cell periphery. May

regulate K8/K18 filament and desmosome organization mainly at the apical or

peripheral regions of simple epithelial cells.
TCHP Sequence databases
EMBL DDBJ GenBank
TCHP 3D structure databases
ModBase
TCHP Protein-protein interaction databases
STRING
TCHP Proteomic databases
PRIDE
TCHP Genome annotation databases
Ensembl GeneID KEGG UCSC
TCHP Organism-specific databases
CTD MGI
TCHP Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
TCHP Gene expression databases
Bgee ArrayExpress Genevestigator
TCHP Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.