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Magnetic Separator
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Human FZD10 (aa 1-581 )
FZD10 Swiss - Prot #
Q9ULW2
FZD10 Protein names
Frizzled-10 (Fz-10) (hFz10) (FzE7) (CD antigen CD350)
FZD10 Gene names
FZD10
Organism
Homo sapiens (Human)
FZD10 Entry name
FZD10_HUMAN

FZD10 Codon-optimized cDNA Clone
FZD10 CDNA Cat#
RPY1418
Tag
cDNA FZD10 contains A 6x histidine tag
Condon optimized FZD10 cDNA Formulation
Liquid
Condon optimized FZD10 cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized FZD10 cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag. 2.

May be used as RNAi assistance to restore the loss-of-function.

Recombinant FZD10 Protein
Recombinant FZD10 Protein Cat#
PY1418
FZD10 Protein Source
Recombinant protein
Recombinant FZD10 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant FZD10 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant FZD10 Protein Activity
N/A
Tag
Recombinant FZD10 contains A 6x histidine tag
Recombinant protein Formulation
Liquid
Recombinant FZD10 protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant FZD10Protein or cDNA
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FZD10’s Protein family
G-protein coupled receptor Fz/Smo family
FZD10’s Subcellular locations
Membrane; Multi-pass membrane protein.
FZD10’s FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: Receptor for Wnt proteins. Most of frizzled receptors are coupled to

the beta-catenin canonical signaling pathway, which leads to the activation of

disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-

catenin and activation of Wnt target genes. A second signaling pathway involving

PKC and calcium fluxes has been seen for some family members, but it is not yet

clear if it represents a distinct pathway or if it can be integrated in the canonical

pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3

kinase. Both pathways seem to involve interactions with G-proteins. May be involved

in transduction and intercellular transmission of polarity information during tissue

morphogenesis and/or in differentiated tissues.
FZD10 Sequence databases
EMBL DDBJ GenBank
FZD10 3D structure databases
ModBase
FZD10’s Protein-protein interaction databases
STRING
FZD10’s Proteomic databases
PRIDE
FZD10’s Genome annotation databases
Ensembl GeneID KEGG UCSC
FZD10’s Organism-specific databases
CTD MGI
FZD10’s Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
FZD10’s Gene expression databases
Bgee ArrayExpress Genevestigator
FZD10’s Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.