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Mouse Fnbp1 (aa 1-616 )
Fnbp1 Swiss - Prot #
Q80TY0
Fnbp1 Protein names
Formin-binding protein 1 (Formin-binding protein 17)
Fnbp1 Gene names
Fnbp1 Fbp17 Kiaa0554
Organism
Mus musculus (Mouse)
Fnbp1 Entry name
FNBP1_MOUSE

Fnbp1 Codon-optimized cDNA Clone
Fnbp1 CDNA Cat#
RPY1528
Tag
cDNA Fnbp1 contains A 6x histidine tag
Condon optimized Fnbp1 cDNA Formulation
Liquid
Condon optimized Fnbp1 cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized Fnbp1 cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag. 2.

May be used as RNAi assistance to restore the loss-of-function.

Recombinant Fnbp1 Protein
Recombinant Fnbp1 Protein Cat#
PY1528
Fnbp1 Protein Source
Recombinant protein
Recombinant Fnbp1 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Fnbp1 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Fnbp1 Protein Activity
N/A
Tag
Recombinant Fnbp1 contains A 6x histidine tag
Recombinant Fnbp1 protein Formulation
Liquid
Recombinant Fnbp1 protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant Fnbp1Protein or cDNA
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Fnbp1’s Protein family
FNBP1 family
Fnbp1’s Subcellular locations
Cytoplasm. Cytoplasm > cytoskeleton. Cytoplasm > cell cortex. Lysosome. Cytoplasmic vesicle. Cell

membrane; Peripheral membrane protein; Cytoplasmic side.
Fnbp1’s FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: Required to coordinate membrane tubulation with reorganization of

the actin cytoskeleton during endocytosis. Binds to lipids such as

phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes

membrane invagination and the formation of tubules. Also enhances actin

polymerization via the recruitment of WASL/N-WASP, which in turn activates the

Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules

to form endocytic vesicles. May act as a link between RND2 signaling and

regulation of the actin cytoskeleton. May be required for the lysosomal retention of

FASLG/FASL (By similarity).
Fnbp1 Sequence databases
EMBL DDBJ GenBank
Fnbp1 3D structure databases
ModBase
Fnbp1’s Protein-protein interaction databases
STRING
Fnbp1’s Proteomic databases
PRIDE
Fnbp1’s Genome annotation databases
Ensembl GeneID KEGG UCSC
Fnbp1’s Organism-specific databases
CTD MGI
Fnbp1’s Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
Fnbp1’s Gene expression databases
Bgee ArrayExpress Genevestigator
Fnbp1’s Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.