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Human RACGAP1 (aa 1-632 )
RACGAP1 Swiss - Prot #
Q9H0H5
RACGAP1 Protein names
Rac GTPase-activating protein 1 (Male germ cell RacGap) (MgcRacGAP)
RACGAP1 Gene names
RACGAP1 KIAA1478 MGCRACGAP
Organism
Homo sapiens (Human)
RACGAP1 Entry name
RGAP1_HUMAN

RACGAP1 Codon-optimized cDNA Clone
RACGAP1 CDNA Cat#
RPY1564
Tag
cDNA RACGAP1 contains A 6x histidine tag
Condon optimized RACGAP1 cDNA Formulation
Liquid
Condon optimized RACGAP1 cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized RACGAP1 cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag. 2.

May be used as RNAi assistance to restore the loss-of-function.

Recombinant RACGAP1 Protein
Recombinant RACGAP1 Protein Cat#
PY1564
RACGAP1 Protein Source
Recombinant protein
Recombinant RACGAP1 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant RACGAP1 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant RACGAP1 Protein Activity
N/A
Tag
Recombinant RACGAP1 contains A 6x histidine tag
Recombinant RACGAP1 protein Formulation
Liquid
Recombinant RACGAP1 protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant RACGAP1Protein or cDNA
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RACGAP1’s Protein family
RACGAP1’s Subcellular locations
Nucleus. Cytoplasm. Cytoplasm > cytoskeleton > spindle. Cytoplasmic vesicle > secretory vesicle >

acrosome.
RACGAP1’s FUNCTION (According to UniProtKB/Swiss-
FUNCTION: Essential for the early stages of embryogenesis and may play a role in
Prot)
the microtubule-dependent steps in cytokinesis. Plays key roles in controlling cell

growth and differentiation of hematopoietic cells through mechanisms other than

regulating Rac GTPase activity. Also involved in the regulation of growth-related

processes in adipocytes and myoblasts. May be involved in regulating

spermatogenesis and in the RACGAP1 pathway in neuronal proliferation. Shows

strong GAP (GTPase activation) activity towards CDC42 and RAC1 and less

towards RHOA. Required for initiation of cleavage furrow ingression by regulating

ECT2 and for assembly of the contractile ring. May play a role in regulating cortical

activity through RHOA during cytokinesis. May participate in the regulation of

sulfate transport in male germ cells.
RACGAP1 Sequence databases
EMBL DDBJ GenBank
RACGAP1 3D structure databases
ModBase
RACGAP1’s Protein-protein interaction databases
STRING
RACGAP1’s Proteomic databases
PRIDE
RACGAP1’s Genome annotation databases
Ensembl GeneID KEGG UCSC
RACGAP1’s Organism-specific databases
CTD MGI
RACGAP1’s Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
RACGAP1’s Gene expression databases
Bgee ArrayExpress Genevestigator
RACGAP1’s Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.