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Mouse Pias1 (aa 1-651 )
Pias1 Swiss - Prot #
O88907
Pias1 Protein names
E3 SUMO-protein ligase PIAS1 (DEAD/H box-binding protein 1) (Protein inhibitor of

activated STAT protein 1)
Pias1 Gene names
Pias1 Ddxbp1
Organism
Mus musculus (Mouse)
Pias1 Entry name
PIAS1_MOUSE

Pias1 Codon-optimized cDNA Clone
Pias1 CDNA Cat#
RPY1607
Tag
cDNA Pias1 contains A 6x histidine tag
Condon optimized Pias1 cDNA Formulation
Liquid
Condon optimized Pias1 cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized Pias1 cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag. 2.

May be used as RNAi assistance to restore the loss-of-function.

Recombinant Pias1 Protein
Recombinant Pias1 Protein Cat#
PY1607
Pias1 Protein Source
Recombinant protein
Recombinant Pias1 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Pias1 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Pias1 Protein Activity
N/A
Tag
Recombinant Pias1 contains A 6x histidine tag
Recombinant Pias1 protein Formulation
Liquid
Recombinant Pias1 protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant Pias1Protein or cDNA
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Pias1’s Protein family
PIAS family
Pias1’s Subcellular locations
Nucleus speckle.
Pias1’s FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase,

stabilizing the interaction between UBE2I and the substrate, and as a SUMO-

tethering factor. Plays a crucial role as a transcriptional coregulation in various

cellular pathways, including the STAT pathway, the p53 pathway and the steroid

hormone signaling pathway. In vitro, binds A/T-rich DNA (By similarity). The effects

of this transcriptional coregulation, transactivation or silencing, may vary

depending upon the biological context. Together with PRMT1, may repress STAT1

transcriptional activity, in the late phase of interferon gamma (IFN-gamma)

signaling.
Pias1 Sequence databases
EMBL DDBJ GenBank
Pias1 3D structure databases
ModBase
Pias1’s Protein-protein interaction databases
STRING
Pias1’s Proteomic databases
PRIDE
Pias1’s Genome annotation databases
Ensembl GeneID KEGG UCSC
Pias1’s Organism-specific databases
CTD MGI
Pias1’s Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
Pias1’s Gene expression databases
Bgee ArrayExpress Genevestigator
Pias1’s Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.