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Human NUP85 (aa 1-656 )
NUP85 Swiss - Prot #
Q9BW27
NUP85 Protein names
Nuclear pore complex protein Nup85 (85 kDa nucleoporin) (FROUNT) (Nucleoporin Nup75)

(Nucleoporin Nup85) (Pericentrin-1)
NUP85 Gene names
NUP85 NUP75 PCNT1
Organism
Homo sapiens (Human)
NUP85 Entry name
NUP85_HUMAN

NUP85 Codon-optimized cDNA Clone
NUP85 CDNA Cat#
RPY1614
Tag
cDNA NUP85 contains A 6x histidine tag
Condon optimized NUP85 cDNA Formulation
Liquid
Condon optimized NUP85 cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized NUP85 cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag. 2.

May be used as RNAi assistance to restore the loss-of-function.

Recombinant NUP85 Protein
Recombinant NUP85 Protein Cat#
PY1614
NUP85 Protein Source
Recombinant protein
Recombinant NUP85 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant NUP85 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant NUP85 Protein Activity
N/A
Tag
Recombinant NUP85 contains A 6x histidine tag
Recombinant NUP85 protein Formulation
Liquid
Recombinant NUP85 protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant NUP85Protein or cDNA
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NUP85’s Protein family
Nucleoporin Nup85 family
NUP85’s Subcellular locations
Nucleus > nuclear pore complex. Chromosome > centromere > kinetochore. Cytoplasm > cytoskeleton

> spindle. Cytoplasm. Nucleus membrane.
NUP85’s FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: Essential component of the nuclear pore complex (NPC) that seems

to be required for NPC assembly and maintenance. As part of the NPC Nup107-

160 subcomplex plays a role in RNA export and in tethering NUP98/Nup98 and

NUP153 to the nucleus. The Nup107-160 complex seems to be required for spindle

assembly during mitosis. NUP85 is required for membrane clustering of CCL2-

activated CCR2. Seems to be involved in CCR2-mediated chemotaxis of monocytes

and may link activated CCR2 to the phosphatidyl-inositol-3-kinase-Rac-

lammellipodium protrusion cascade.
NUP85 Sequence databases
EMBL DDBJ GenBank
NUP85 3D structure databases
ModBase
NUP85’s Protein-protein interaction databases
STRING
NUP85’s Proteomic databases
PRIDE
NUP85’s Genome annotation databases
Ensembl GeneID KEGG UCSC
NUP85’s Organism-specific databases
CTD MGI
NUP85’s Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
NUP85’s Gene expression databases
Bgee ArrayExpress Genevestigator
NUP85’s Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.