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Human SCIN (aa 1-715 )
SCIN Swiss - Prot #
Q9Y6U3
SCIN Protein names
Adseverin (Scinderin)
SCIN Gene names
SCIN KIAA1905
Organism
Homo sapiens (Human)
SCIN Entry name
ADSV_HUMAN

SCIN Codon-optimized cDNA Clone
SCIN CDNA Cat#
RPY1752
Tag
cDNA SCIN contains A 6x histidine tag
Condon optimized SCIN cDNA Formulation
Liquid
Condon optimized SCIN cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized SCIN cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag. 2.

May be used as RNAi assistance to restore the loss-of-function.

Recombinant SCIN Protein
Recombinant SCIN Protein Cat#
PY1752
SCIN Protein Source
Recombinant protein
Recombinant SCIN Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant SCIN Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant SCIN Protein Activity
N/A
Tag
Recombinant SCIN contains A 6x histidine tag
Recombinant SCIN protein Formulation
Liquid
Recombinant SCIN protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant SCINProtein or cDNA
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SCIN’s Protein family
Villin/gelsolin family
SCIN’s Subcellular locations
Cytoplasm > cytoskeleton.
SCIN’s FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: Ca(2+)-dependent actin filament-severing protein that is presumed to

have a regulatory function in exocytosis by affecting the organization of the

microfilament network underneath the plasma membrane. In vitro, also has barbed

end capping and nucleating activities in the presence of Ca(2+). Regulates

chondrocyte proliferation and differentiation. MAP kinases p38 and ERK1/2 mediate

the adseverin-induced accelerated differentiation of non-hypertrophic chondrocytes

(By similarity).
SCIN Sequence databases
EMBL DDBJ GenBank
SCIN 3D structure databases
ModBase
SCIN’s Protein-protein interaction databases
STRING
SCIN’s Proteomic databases
PRIDE
SCIN’s Genome annotation databases
Ensembl GeneID KEGG UCSC
SCIN’s Organism-specific databases
CTD MGI
SCIN’s Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
SCIN’s Gene expression databases
Bgee ArrayExpress Genevestigator
SCIN’s Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.