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Human DLG4 (aa 1-724 )
DLG4 Swiss - Prot #
P78352
DLG4 Protein names
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated

protein 90) (SAP-90) (SAP90)
DLG4 Gene names
DLG4 PSD95
Organism
Homo sapiens (Human)
DLG4 Entry name
DLG4_HUMAN

DLG4 Codon-optimized cDNA Clone
DLG4 CDNA Cat#
RPY1780
Tag
cDNA DLG4 contains A 6x histidine tag
Condon optimized DLG4 cDNA Formulation
Liquid
Condon optimized DLG4 cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized DLG4 cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag. 2.

May be used as RNAi assistance to restore the loss-of-function.

Recombinant DLG4 Protein
Recombinant DLG4 Protein Cat#
PY1780
DLG4 Protein Source
Recombinant protein
Recombinant DLG4 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant DLG4 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant DLG4 Protein Activity
N/A
Tag
Recombinant DLG4 contains A 6x histidine tag
Recombinant DLG4 protein Formulation
Liquid
Recombinant DLG4 protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant DLG4Protein or cDNA
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DLG4’s Protein family
MAGUK family
DLG4’s Subcellular locations
Cell membrane; Peripheral membrane protein. Cell junction > synapse > postsynaptic cell membrane

> postsynaptic density. Cell junction > synapse. Cell junction > synapse > synaptosome.
DLG4’s FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: Interacts with the cytoplasmic tail of NMDA receptor subunits and

shaker-type potassium channels. Required for synaptic plasticity associated with

NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio

of excitatory to inhibitory synapses in hippocampal neurons. May reduce the

amplitude of ACCN3 acid-evoked currents by retaining the channel intracellularly.

May regulate the intracellular trafficking of ADR1B (By similarity).
DLG4 Sequence databases
EMBL DDBJ GenBank
DLG4 3D structure databases
ModBase
DLG4’s Protein-protein interaction databases
STRING
DLG4’s Proteomic databases
PRIDE
DLG4’s Genome annotation databases
Ensembl GeneID KEGG UCSC
DLG4’s Organism-specific databases
CTD MGI
DLG4’s Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
DLG4’s Gene expression databases
Bgee ArrayExpress Genevestigator
DLG4’s Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.