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Human PPP1R9B (aa 1-815 )
PPP1R9B Swiss - Prot #
Q96SB3
PPP1R9B Protein names
Neurabin-2 (Neurabin-II) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin)
PPP1R9B Gene names
PPP1R9B PPP1R6
Organism
Homo sapiens (Human)
PPP1R9B Entry name
NEB2_HUMAN

PPP1R9B Codon-optimized cDNA Clone
PPP1R9B CDNA Cat#
RPY1956
Tag
cDNA PPP1R9B contains A 6x histidine tag
Condon optimized PPP1R9B cDNA Formulation
Liquid
Condon optimized PPP1R9B cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized PPP1R9B cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag. 2.

May be used as RNAi assistance to restore the loss-of-function.

Recombinant PPP1R9B Protein
Recombinant PPP1R9B Protein Cat#
PY1956
PPP1R9B Protein Source
Recombinant protein
Recombinant PPP1R9B Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant PPP1R9B Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant PPP1R9B Protein Activity
N/A
Tag
Recombinant PPP1R9B contains A 6x histidine tag
Recombinant PPP1R9B protein Formulation
Liquid
Recombinant PPP1R9B protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant PPP1R9BProtein or cDNA
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PPP1R9B’s Protein family
PPP1R9B’s Subcellular locations
Cytoplasm > cytoskeleton. Nucleus. Cell projection > dendritic spine. Cell junction > synapse.
PPP1R9B’s FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: Seems to act as a scaffold protein in multiple signaling pathways.

Modulates excitatory synaptic transmission and dendritic spine morphology. Binds

to actin filaments (F-actin) and shows cross-linking activity. Binds along the sides

of the F-actin. May play an important role in linking the actin cytoskeleton to the

plasma membrane at the synaptic junction. Believed to target protein phosphatase

1/PP1 to dendritic spines, which are rich in F-actin, and regulates its specificity

toward ion channels and other substrates, such as AMPA-type and NMDA-type

glutamate receptors. Plays a role in regulation of G-protein coupled receptor

signaling, including dopamine D2 receptors and alpha-adrenergic receptors. May

establish a signaling complex for dopaminergic neurotransmission through D2

receptors by linking receptors downstream signaling molecules and the actin

cytoskeleton. Binds to ADRA1B and RGS2 and mediates regulation of ADRA1B

signaling. May confer to Rac signaling specificity by binding to both, RacGEFs

and Rac effector proteins. Probably regulates p70 S6 kinase activity by forming a

complex with TIAM1 (By similarity).
PPP1R9B Sequence databases
EMBL DDBJ GenBank
PPP1R9B 3D structure databases
ModBase
PPP1R9B’s Protein-protein interaction databases
STRING
PPP1R9B’s Proteomic databases
PRIDE
PPP1R9B’s Genome annotation databases
Ensembl GeneID KEGG UCSC
PPP1R9B’s Organism-specific databases
CTD MGI
PPP1R9B’s Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
PPP1R9B’s Gene expression databases
Bgee ArrayExpress Genevestigator
PPP1R9B’s Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.