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Mouse Smek1 (aa 1-820 )
Smek1 Swiss - Prot #
Q6P2K6
Smek1 Protein names
Serine/threonine-protein phosphatase 4 regulatory subunit 3A (SMEK homolog 1)
Smek1 Gene names
Smek1 Kiaa2010 Pp4r3a Ppp4r3a
Organism
Mus musculus (Mouse)
Smek1 Entry name
P4R3A_MOUSE

Smek1 Codon-optimized cDNA Clone
Smek1 CDNA Cat#
RPY1966
Tag
cDNA Smek1 contains A 6x histidine tag
Condon optimized Smek1 cDNA Formulation
Liquid
Condon optimized Smek1 cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized Smek1 cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag. 2.

May be used as RNAi assistance to restore the loss-of-function.

Recombinant Smek1 Protein
Recombinant Smek1 Protein Cat#
PY1966
Smek1 Protein Source
Recombinant protein
Recombinant Smek1 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Smek1 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Smek1 Protein Activity
N/A
Tag
Recombinant Smek1 contains A 6x histidine tag
Recombinant Smek1 protein Formulation
Liquid
Recombinant Smek1 protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant Smek1Protein or cDNA
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Smek1’s Protein family
SMEK family
Smek1’s Subcellular locations
Cytoplasm. Cytoplasm > cytoskeleton > centrosome. Nucleus.
Smek1’s FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: Regulatory subunit of serine/threonine-protein phosphatase 4. May

regulate the activity of PPP4C at centrosomal microtubule organizing centers. The

PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX

phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication

and required for DNA DSB repair (By similarity).
Smek1 Sequence databases
EMBL DDBJ GenBank
Smek1 3D structure databases
ModBase
Smek1’s Protein-protein interaction databases
STRING
Smek1’s Proteomic databases
PRIDE
Smek1’s Genome annotation databases
Ensembl GeneID KEGG UCSC
Smek1’s Organism-specific databases
CTD MGI
Smek1’s Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
Smek1’s Gene expression databases
Bgee ArrayExpress Genevestigator
Smek1’s Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.