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Human RNF19A (aa 1-838 )
RNF19A Swiss - Prot #
Q9NV58
RNF19A Protein names
E3 ubiquitin-protein ligase RNF19A (EC 6.3.2.-) (Double ring-finger protein) (Dorfin) (RING

finger protein 19A) (p38)
RNF19A Gene names
RNF19A RNF19
Organism
Homo sapiens (Human)
RNF19A Entry name
RN19A_HUMAN

RNF19A Codon-optimized cDNA Clone
RNF19A CDNA Cat#
RPY1999
Tag
cDNA RNF19A contains A 6x histidine tag
Condon optimized RNF19A cDNA Formulation
Liquid
Condon optimized RNF19A cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized RNF19A cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag. 2.

May be used as RNAi assistance to restore the loss-of-function.

Recombinant RNF19A Protein
Recombinant RNF19A Protein Cat#
PY1999
RNF19A Protein Source
Recombinant protein
Recombinant RNF19A Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant RNF19A Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant RNF19A Protein Activity
N/A
Tag
Recombinant RNF19A contains A 6x histidine tag
Recombinant RNF19A protein Formulation
Liquid
Recombinant RNF19A protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant RNF19AProtein or cDNA
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RNF19A’s Protein family
RBR family, RNF19 subfamily
RNF19A’s Subcellular locations
Membrane; Multi-pass membrane protein. Cytoplasm > cytoskeleton > centrosome.
RNF19A’s FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-

conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then

directly transfers the ubiquitin to targeted substrates, such as SNCAIP or CASR.

Specifically ubiquitinates pathogenic SOD1 variants, which leads to their

proteasomal degradation and to neuronal protection.
RNF19A Sequence databases
EMBL DDBJ GenBank
RNF19A 3D structure databases
ModBase
RNF19A’s Protein-protein interaction databases
STRING
RNF19A’s Proteomic databases
PRIDE
RNF19A’s Genome annotation databases
Ensembl GeneID KEGG UCSC
RNF19A’s Organism-specific databases
CTD MGI
RNF19A’s Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
RNF19A’s Gene expression databases
Bgee ArrayExpress Genevestigator
RNF19A’s Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.