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Rat Pdcd6ip (aa 1-873 )
Pdcd6ip Swiss - Prot #
Q9QZA2
Pdcd6ip Protein names
Programmed cell death 6-interacting protein (ALG-2-interacting protein 1)
Pdcd6ip Gene names
Pdcd6ip Aip1
Organism
Rattus norvegicus (Rat)
Pdcd6ip Entry name
PDC6I_RAT

Pdcd6ip Codon-optimized cDNA Clone
Pdcd6ip CDNA Cat#
RPY2056
Tag
cDNA Pdcd6ip contains A 6x histidine tag
Condon optimized Pdcd6ip cDNA Formulation
Liquid
Condon optimized Pdcd6ip cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized Pdcd6ip cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag. 2.

May be used as RNAi assistance to restore the loss-of-function.

Recombinant Pdcd6ip Protein
Recombinant Pdcd6ip Protein Cat#
PY2056
Pdcd6ip Protein Source
Recombinant protein
Recombinant Pdcd6ip Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Pdcd6ip Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Pdcd6ip Protein Activity
N/A
Tag
Recombinant Pdcd6ip contains A 6x histidine tag
Recombinant Pdcd6ip protein Formulation
Liquid
Recombinant Pdcd6ip protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant Pdcd6ipProtein or cDNA
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Pdcd6ip’s Protein family
Pdcd6ip’s Subcellular locations
Melanosome. Cytoplasm > cytoskeleton > centrosome. Cytoplasm > cytosol.
Pdcd6ip’s FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: Class E VPS protein involved in concentration and sorting of cargo

proteins of the multivesicular body (MVB) for incorporation into intralumenal

vesicles (ILVs) that are generated by invagination and scission from the limiting

membrane of the endosome. Binds to the phospholipid lysobisphosphatidic acid

(LBPA) which is abundant in MVBs internal membranes. The MVB pathway

appears to require the sequential function of ESCRT-O, -I,-II and -III complexes.

The ESCRT machinery also functions in topologically equivalent membrane fission

events, such as the terminal stages of cytokinesis. Appears to be an adapter for a

subset of ESCRT-III proteins, such as CHMP4, to function at distinct membranes.

Required for completion of cytokinesis. May play a role in the regulation of both

apoptosis and cell proliferation.
Pdcd6ip Sequence databases
EMBL DDBJ GenBank
Pdcd6ip 3D structure databases
ModBase
Pdcd6ip’s Protein-protein interaction databases
STRING
Pdcd6ip’s Proteomic databases
PRIDE
Pdcd6ip’s Genome annotation databases
Ensembl GeneID KEGG UCSC
Pdcd6ip’s Organism-specific databases
CTD MGI
Pdcd6ip’s Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
Pdcd6ip’s Gene expression databases
Bgee ArrayExpress Genevestigator
Pdcd6ip’s Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.