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RAT Med28 (aa 1-178 )
Med28 Swiss-Prot #
P68943
Med28 Protein names
Mediator of RNA polymerase II transcription subunit 28 (Mediator complex subunit 28)
Med28 Gene names
Med28
Organism
Rattus norvegicus (Rat)
Med28 Entry name
MED28_RAT

Med28 Codon-optimized cDNA Clone
Med28 CDNA Cat#
RPY0208
Tag
cDNA Med28 contains A 6x histidine tag
Condon optimized Med28 cDNA Formulation
Liquid
Condon optimized Med28 cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized Med28 cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag. 2.

May be used as RNAi assistance to restore the loss-of-function.

Recombinant Med28 Protein
Recombinant Med28 Protein Cat#
PY0208
Med28 Protein Source
Recombinant protein
Recombinant Med28 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Med28 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Med28 Protein Activity
N/A
Tag
Recombinant Med28 contains A 6x histidine tag
Condon optimized Med28 cDNA Formulation
Liquid
Condon optimized Med28 cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant Med28 Protein or cDNA
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Med28 Protein family
Mediator complex subunit 28 family
Med28 Subcellular locations
Nucleus. Cytoplasm. Membrane.
Med28 FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: May be part of a complex containing NF2/merlin that participates in

cellular signaling to the actin cytoskeleton downstream of tyrosine kinase signaling

pathways (By similarity). Component of the Mediator complex, a coactivator involved

in the regulated transcription of nearly all RNA polymerase II-dependent genes.

Mediator functions as a bridge to convey information from gene-specific regulatory

proteins to the basal RNA polymerase II transcription machinery. Mediator is

recruited to promoters by direct interactions with regulatory proteins and serves as

a scaffold for the assembly of a functional preinitiation complex with RNA

polymerase II and the general transcription factors.
Med28 Sequence databases
EMBL DDBJ GenBank
Med28 3D structure databases
ModBase
Med28 Protein-protein interaction databases
STRING
Med28 Proteomic databases
PRIDE
Med28 Genome annotation databases
Ensembl GeneID KEGG UCSC
Med28 Organism-specific databases
CTD MGI
Med28 Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
Med28 Gene expression databases
Bgee ArrayExpress Genevestigator
Med28 Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.