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Mouse Dag1 (aa 1-893 )
Dag1 Swiss - Prot #
Q62165
Dag1 Protein names
Dystroglycan (Dystrophin-associated glycoprotein 1) [Cleaved into: Alpha-dystroglycan

(Alpha-DG); Beta-dystroglycan (Beta-DG)]
Dag1 Gene names
Dag1 Dag-1
Organism
Mus musculus (Mouse)
Dag1 Entry name
DAG1_MOUSE

Dag1 Codon-optimized cDNA Clone
Dag1 CDNA Cat#
RPY2083
Tag
cDNA Dag1 contains A 6x histidine tag
Condon optimized Dag1 cDNA Formulation
Liquid
Condon optimized Dag1 cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized Dag1 cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag. 2.

May be used as RNAi assistance to restore the loss-of-function.

Recombinant Dag1 Protein
Recombinant Dag1 Protein Cat#
PY2083
Dag1 Protein Source
Recombinant protein
Recombinant Dag1 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Dag1 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Dag1 Protein Activity
N/A
Tag
Recombinant Dag1 contains A 6x histidine tag
Recombinant Dag1 protein Formulation
Liquid
Recombinant Dag1 protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant Dag1Protein or cDNA
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Dag1’s Protein family
Dag1’s Subcellular locations
Secreted > extracellular space. Cell membrane; Single-pass type I membrane protein. Cytoplasm >

cytoskeleton. Nucleus > nucleoplasm.
Dag1’s FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: The dystroglycan complex is involved in a number of processes

including laminin and basement membrane assembly, sacrolemmal stability, cell

survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial

polarization.; FUNCTION: Alpha-dystroglycan is an extracellular peripheral

glycoprotein that acts as a receptor for both extracellular matrix proteins containing

laminin-G domains, and for certain adenoviruses. Receptor for laminin-2 (LAMA2)

and agrin in peripheral nerve Schwann cells. Also receptor for lymphocytic

choriomeningitis virus, Old World Lassa fever virus, and clade C New World

arenaviruses.; FUNCTION: Beta-dystroglycan is a transmembrane protein that

plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts

as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for

both DMD and UTRN and, through these interactions, scaffolds axin to the

cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in

cell polarity (By similarity).
Dag1 Sequence databases
EMBL DDBJ GenBank
Dag1 3D structure databases
ModBase
Dag1’s Protein-protein interaction databases
STRING
Dag1’s Proteomic databases
PRIDE
Dag1’s Genome annotation databases
Ensembl GeneID KEGG UCSC
Dag1’s Organism-specific databases
CTD MGI
Dag1’s Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
Dag1’s Gene expression databases
Bgee ArrayExpress Genevestigator
Dag1’s Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.