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Human MCF2 (aa 1-925 )
MCF2 Swiss - Prot #
P10911
MCF2 Protein names
Proto-oncogene DBL (Proto-oncogene MCF-2) [Cleaved into: MCF2-transforming protein;

DBL-transforming protein]
MCF2 Gene names
MCF2 DBL
Organism
Homo sapiens (Human)
MCF2 Entry name
MCF2_HUMAN

MCF2 Codon-optimized cDNA Clone
MCF2 CDNA Cat#
RPY2132
Tag
cDNA MCF2 contains A 6x histidine tag
Condon optimized MCF2 cDNA Formulation
Liquid
Condon optimized MCF2 cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized MCF2 cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag. 2.

May be used as RNAi assistance to restore the loss-of-function.

Recombinant MCF2 Protein
Recombinant MCF2 Protein Cat#
PY2132
MCF2 Protein Source
Recombinant protein
Recombinant MCF2 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant MCF2 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant MCF2 Protein Activity
N/A
Tag
Recombinant MCF2 contains A 6x histidine tag
Recombinant MCF2 protein Formulation
Liquid
Recombinant MCF2 protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant MCF2Protein or cDNA
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MCF2’s Protein family
MCF2 family
MCF2’s Subcellular locations
Cytoplasm. Membrane.
MCF2’s FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: Guanine nucleotide exchange factor (GEF) that modulates the Rho

family of GTPases. Promotes the conversion of some member of the Rho family

GTPase from the GDP-bound to the GTP-bound form. Isoform 1 exhibits no activity

toward RHOA, RAC1 or CDC42. Isoform 2 exhibits decreased GEF activity toward

CDC42. Isoform 3 exhibits a weak but significant activity toward RAC1 and CDC42.

Isoform 4 exhibits significant activity toward RHOA and CDC42. The truncated

DBL oncogene is active toward RHOA, RAC1 and CDC42.
MCF2 Sequence databases
EMBL DDBJ GenBank
MCF2 3D structure databases
ModBase
MCF2’s Protein-protein interaction databases
STRING
MCF2’s Proteomic databases
PRIDE
MCF2’s Genome annotation databases
Ensembl GeneID KEGG UCSC
MCF2’s Organism-specific databases
CTD MGI
MCF2’s Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
MCF2’s Gene expression databases
Bgee ArrayExpress Genevestigator
MCF2’s Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.