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Rat Tmem67 (aa 1-992 )
Tmem67 Swiss - Prot #
P0C152
Tmem67 Protein names
Meckelin (Meckel syndrome type 3 protein homolog) (Transmembrane protein 67)
Tmem67 Gene names
Tmem67 Mks3 Wpk
Organism
Rattus norvegicus (Rat)
Tmem67 Entry name
MKS3_RAT

Tmem67 Codon-optimized cDNA Clone
Tmem67 CDNA Cat#
RPY2217
Tag
cDNA Tmem67 contains A 6x histidine tag
Condon optimized Tmem67 cDNA Formulation
Liquid
Condon optimized Tmem67 cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized Tmem67 cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag. 2.

May be used as RNAi assistance to restore the loss-of-function.

Recombinant Tmem67 Protein
Recombinant Tmem67 Protein Cat#
PY2217
Tmem67 Protein Source
Recombinant protein
Recombinant Tmem67 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Tmem67 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Tmem67 Protein Activity
N/A
Tag
Recombinant Tmem67 contains A 6x histidine tag
Recombinant Tmem67 protein Formulation
Liquid
Recombinant Tmem67 protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant Tmem67Protein or cDNA
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Tmem67’s Protein family
Tmem67’s Subcellular locations
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass

membrane protein. Cytoplasm > cytoskeleton > cilium basal body.
Tmem67’s FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: Involved in centrosome migration to the apical cell surface during

early ciliogenesis. Required for ciliary structure and function, including a role in

regulating length and appropriate number through modulating centrosome

duplication. Required for cell branching morphology. Essential for endoplasmic

deticulum-associated degradation (ERAD) of surfactant protein C (sftpc) (By

similarity).
Tmem67 Sequence databases
EMBL DDBJ GenBank
Tmem67 3D structure databases
ModBase
Tmem67’s Protein-protein interaction databases
STRING
Tmem67’s Proteomic databases
PRIDE
Tmem67’s Genome annotation databases
Ensembl GeneID KEGG UCSC
Tmem67’s Organism-specific databases
CTD MGI
Tmem67’s Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
Tmem67’s Gene expression databases
Bgee ArrayExpress Genevestigator
Tmem67’s Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.