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Mouse Invs (aa 1-1062 )
Invs Swiss - Prot #
O89019
Invs Protein names
Inversin (Inversion of embryo turning protein) (Nephrocystin-2)
Invs Gene names
Invs Inv Nphp2
Organism
Mus musculus (Mouse)
Invs Entry name
INVS_MOUSE

Invs Codon-optimized cDNA Clone
Invs CDNA Cat#
RPY2286
Tag
cDNA Invs contains A 6x histidine tag
Condon optimized Invs cDNA Formulation
Liquid
Condon optimized Invs cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized Invs cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag. 2.

May be used as RNAi assistance to restore the loss-of-function.

Recombinant Invs Protein
Recombinant Invs Protein Cat#
PY2286
Invs Protein Source
Recombinant protein
Recombinant Invs Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Invs Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Invs Protein Activity
N/A
Tag
Recombinant Invs contains A 6x histidine tag
Recombinant Invs protein Formulation
Liquid
Recombinant Invs protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant InvsProtein or cDNA
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Invs’s Protein family
Invs’s Subcellular locations
Cytoplasm. Cytoplasm > cytoskeleton. Membrane; Peripheral membrane protein. Nucleus. Cytoplasm

> perinuclear region. Cytoplasm > cytoskeleton > spindle.
Invs’s FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: Required for normal renal development and establishment of left-right

axis. Probably acts as a molecular switch between different Wnt signaling

pathways. Inhibits the canonical Wnt pathway by targeting cytoplasmic disheveled

(DVL1) for degradation by the ubiquitin-proteasome. This suggests that it is

required in renal development to oppose the repression of terminal differentiation of

tubular epithelial cells by Wnt signaling (By similarity).
Invs Sequence databases
EMBL DDBJ GenBank
Invs 3D structure databases
ModBase
Invs’s Protein-protein interaction databases
STRING
Invs’s Proteomic databases
PRIDE
Invs’s Genome annotation databases
Ensembl GeneID KEGG UCSC
Invs’s Organism-specific databases
CTD MGI
Invs’s Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
Invs’s Gene expression databases
Bgee ArrayExpress Genevestigator
Invs’s Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.