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Mouse Eif3a (aa 1-1344 )
Eif3a Swiss - Prot #
P23116
Eif3a Protein names
Eukaryotic translation initiation factor 3 subunit A (eIF3a) (Centrosomin) (Eukaryotic

translation initiation factor 3 subunit 10) (eIF-3-theta) (eIF3 p167) (eIF3 p180) (eIF3 p185)

(p162)
Eif3a Gene names
Eif3a Csma Eif3 Eif3s10
Organism
Mus musculus (Mouse)
Eif3a Entry name
EIF3A_MOUSE

Eif3a Codon-optimized cDNA Clone
Eif3a CDNA Cat#
RPY2466
Tag
cDNA Eif3a contains A 6x histidine tag
Condon optimized Eif3a cDNA Formulation
Liquid
Condon optimized Eif3a cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized Eif3a cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag. 2.

May be used as RNAi assistance to restore the loss-of-function.

Recombinant Eif3a Protein
Recombinant Eif3a Protein Cat#
PY2466
Eif3a Protein Source
Recombinant protein
Recombinant Eif3a Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Eif3a Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Eif3a Protein Activity
N/A
Tag
Recombinant Eif3a contains A 6x histidine tag
Recombinant Eif3a protein Formulation
Liquid
Recombinant Eif3a protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
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Eif3a’s Protein family
EIF-3 subunit A family
Eif3a’s Subcellular locations
Cytoplasm. Cytoplasm > cytoskeleton > centrosome. Nucleus.
Eif3a’s FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: Component of the eukaryotic translation initiation factor 3 (eIF-3)

complex, which is required for several steps in the initiation of protein synthesis.

The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment

of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation

complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S

PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also

required for disassembly and recycling of posttermination ribosomal complexes and

subsequently prevents premature joining of the 40S and 60S ribosomal subunits

prior to initiation.
Eif3a Sequence databases
EMBL DDBJ GenBank
Eif3a 3D structure databases
ModBase
Eif3a’s Protein-protein interaction databases
STRING
Eif3a’s Proteomic databases
PRIDE
Eif3a’s Genome annotation databases
Ensembl GeneID KEGG UCSC
Eif3a’s Organism-specific databases
CTD MGI
Eif3a’s Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
Eif3a’s Gene expression databases
Bgee ArrayExpress Genevestigator
Eif3a’s Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.