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Rat Insr (aa 1-1383 )
Insr Swiss - Prot #
P15127
Insr Protein names
Insulin receptor (IR) (EC 2.7.10.1) (CD antigen CD220) [Cleaved into: Insulin receptor

subunit alpha; Insulin receptor subunit beta]
Insr Gene names
Insr
Organism
Rattus norvegicus (Rat)
Insr Entry name
INSR_RAT

Insr Codon-optimized cDNA Clone
Insr CDNA Cat#
RPY2476
Tag
cDNA Insr contains A 6x histidine tag
Condon optimized Insr cDNA Formulation
Liquid
Condon optimized Insr cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized Insr cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag. 2.

May be used as RNAi assistance to restore the loss-of-function.

Recombinant Insr Protein
Recombinant Insr Protein Cat#
PY2476
Insr Protein Source
Recombinant protein
Recombinant Insr Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Insr Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Insr Protein Activity
N/A
Tag
Recombinant Insr contains A 6x histidine tag
Recombinant Insr protein Formulation
Liquid
Recombinant Insr protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant InsrProtein or cDNA
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Insr’s Protein family
Protein kinase superfamily, Tyr protein kinase family, Insulin receptor subfamily
Insr’s Subcellular locations
Membrane; Single-pass type I membrane protein.
Insr’s FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: This receptor binds insulin and has a tyrosine-protein kinase activity.

Isoform Short has a higher affinity for insulin. Mediates the metabolic functions of

insulin. Binding to insulin stimulates association of the receptor with downstream

mediators including IRS1 and phosphatidylinositol 3'-kinase (PI3K).
Insr Sequence databases
EMBL DDBJ GenBank
Insr 3D structure databases
ModBase
Insr’s Protein-protein interaction databases
STRING
Insr’s Proteomic databases
PRIDE
Insr’s Genome annotation databases
Ensembl GeneID KEGG UCSC
Insr’s Organism-specific databases
CTD MGI
Insr’s Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
Insr’s Gene expression databases
Bgee ArrayExpress Genevestigator
Insr’s Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.