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Human LRPPRC (aa 1-1394 )
LRPPRC Swiss - Prot #
P42704
LRPPRC Protein names
Leucine-rich PPR motif-containing protein, mitochondrial (130 kDa leucine-rich protein)

(LRP 130) (GP130)
LRPPRC Gene names
LRPPRC LRP130
Organism
Homo sapiens (Human)
LRPPRC Entry name
LPPRC_HUMAN

LRPPRC Codon-optimized cDNA Clone
LRPPRC CDNA Cat#
RPY2483
Tag
cDNA LRPPRC contains A 6x histidine tag
Condon optimized LRPPRC cDNA Formulation
Liquid
Condon optimized LRPPRC cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized LRPPRC cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag. 2.

May be used as RNAi assistance to restore the loss-of-function.

Recombinant LRPPRC Protein
Recombinant LRPPRC Protein Cat#
PY2483
LRPPRC Protein Source
Recombinant protein
Recombinant LRPPRC Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant LRPPRC Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant LRPPRC Protein Activity
N/A
Tag
Recombinant LRPPRC contains A 6x histidine tag
Recombinant LRPPRC protein Formulation
Liquid
Recombinant LRPPRC protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant LRPPRCProtein or cDNA
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LRPPRC’s Protein family
LRPPRC’s Subcellular locations
Mitochondrion. Nucleus > nucleoplasm. Nucleus inner membrane. Nucleus outer membrane.
LRPPRC’s FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: May play a role in RNA metabolism in both nuclei and mitochondria.

In the nucleus binds to HNRPA1-associated poly(A) mRNAs and is part of nmRNP

complexes at late stages of mRNA maturation which are possibly associated with

nuclear mRNA export. May bind mature mRNA in the nucleus outer membrane. In

mitochondria binds to poly(A) mRNA. Plays a role in translation or stability of

mitochondrially encoded cytochrome c oxidase (COX) subunits. May be involved in

transcription regulation. Cooperates with PPARGC1A to regulate certain

mitochondrially encoded genes and gluconeogenic genes and may regulate

docking of PPARGC1A to transcription factors. Seems to be involved in the

transcription regulation of the multidrug-related genes MDR1 and MVP. Part of a

nuclear factor that binds to the invMED1 element of MDR1 and MVP gene

promoters. Binds single-stranded DNA (By similarity).
LRPPRC Sequence databases
EMBL DDBJ GenBank
LRPPRC 3D structure databases
ModBase
LRPPRC’s Protein-protein interaction databases
STRING
LRPPRC’s Proteomic databases
PRIDE
LRPPRC’s Genome annotation databases
Ensembl GeneID KEGG UCSC
LRPPRC’s Organism-specific databases
CTD MGI
LRPPRC’s Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
LRPPRC’s Gene expression databases
Bgee ArrayExpress Genevestigator
LRPPRC’s Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.