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Rat Dmbt1 (aa 1-1418 )
Dmbt1 Swiss - Prot #
Q8CIZ5
Dmbt1 Protein names
Deleted in malignant brain tumors 1 protein (Ebnerin) (Hensin) (Pancrin)
Dmbt1 Gene names
Dmbt1
Organism
Rattus norvegicus (Rat)
Dmbt1 Entry name
DMBT1_RAT

Dmbt1 Codon-optimized cDNA Clone
Dmbt1 CDNA Cat#
RPY2500
Tag
cDNA Dmbt1 contains A 6x histidine tag
Condon optimized Dmbt1 cDNA Formulation
Liquid
Condon optimized Dmbt1 cDNA Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Condon optimized Dmbt1 cDNA Application (s)
Applications: 1. Codon-optimized cDNA sequence designed for

recombinant protein production in both E.coli and Mammalian cell. The

cDNA has been cloned into E.coli expression vector with 6x Histidine tag. 2.

May be used as RNAi assistance to restore the loss-of-function.

Recombinant Dmbt1 Protein
Recombinant Dmbt1 Protein Cat#
PY2500
Dmbt1 Protein Source
Recombinant protein
Recombinant Dmbt1 Protein Applications
Western Blot, may be used for other applications determined by user
Recombinant Dmbt1 Protein Purity
>90%, as determined by SDS-PAGE under reducing conditions
Recombinant Dmbt1 Protein Activity
N/A
Tag
Recombinant Dmbt1 contains A 6x histidine tag
Recombinant Dmbt1 protein Formulation
Liquid
Recombinant Dmbt1 protein Storage
−20℃ to −70℃. Avoid repeated freeze-thaw cycles.
Place Order for Recombinant Dmbt1Protein or cDNA
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Dmbt1’s Protein family
DMBT1 family
Dmbt1’s Subcellular locations
Secreted. Cytoplasmic vesicle > secretory vesicle membrane; Single-pass membrane protein;

Lumenal side.
Dmbt1’s FUNCTION (According to UniProtKB/Swiss-Prot)
FUNCTION: May play roles in mucosal defense system, cellular immune defense

and epithelial differentiation (By similarity). May play a role in liver regeneration.

May be an important factor in fate decision and differentiation of transit-amplifying

ductular (oval) cells within the hepatic lineage. May function as a binding protein in

saliva for the regulation of taste sensation. May play a role as an opsonin receptor

for SFTPD and SPAR in macrophages tissues throughout the body, including

epithelial cells lining the gastrointestinal tract (By similarity). Required for terminal

differentiation of columnar epithelial cells during early embryogenesis. Displays a

broad calcium-dependent binding spectrum against both Gram-positive and Gram-

negative bacteria, suggesting a role in defense against bacterial pathogens. Binds

to a range of poly-sulfated and poly-phosphorylated ligands which may explain its

broad bacterial-binding specificity. Inhibits cytoinvasion of S.enterica. Associates

with the actin cytoskeleton and is involved in its remodeling during regulated

exocytosis. Interacts with pancreatic zymogens in a pH-dependent manner and may

act as a Golgi cargo receptor in the regulated secretory pathway of the pancreatic

acinar cell (By similarity).
Dmbt1 Sequence databases
EMBL DDBJ GenBank
Dmbt1 3D structure databases
ModBase
Dmbt1’s Protein-protein interaction databases
STRING
Dmbt1’s Proteomic databases
PRIDE
Dmbt1’s Genome annotation databases
Ensembl GeneID KEGG UCSC
Dmbt1’s Organism-specific databases
CTD MGI
Dmbt1’s Phylogenomic databases
eggNOG GeneTree HOGENOM HOVERGEN InParanoid OrthoDB PhylomeDB OMA
Dmbt1’s Gene expression databases
Bgee ArrayExpress Genevestigator
Dmbt1’s Family and domain databases
InterPro PROSITE ProtoNet

FOR in vitro RESEARCH USE ONLY. NOT FOR USE IN HUMANS.